Lithiation and reactions of stilbene oxides: synthetic utility.
Lithiation and reactions of stilbene oxides: synthetic utility.
复制标题
二苯乙烯氧化物的锂化和反应：合成用途。
作者：
S. Florio;V. Aggarwal;A. Salomone
研究了反式和顺式二苯乙烯氧化物（+/-）-1和8的锂化反应。而对于8，锂化仅发生在苄基位置，对于反式异构体（+/-）-1，邻位锂化与α-锂化竞争，这取决于实验条件。证明了α-锂化的顺式-和反式-二苯乙烯氧化物（+/-）-2和（+/-）-9的构型稳定性，以及标位二苯乙烯氧化物（R，R）-2的构型稳定性。
The lithiation of trans- and cis-stilbene oxides (+/-)-1 and 8 has been investigated. While with 8, lithiation occurred exclusively at the benzylic position, with the trans isomer (+/-)-1, ortho-lithiation competed with alpha-lithiation depending upon the experimental conditions. The configurational stability of the alpha-lithiated cis- and trans-stilbene oxides (+/-)-2 and (+/-)-9, respectively, was proved as well as that of scalemic stilbene oxide (R,R)-2.