Use of Mutual Information and Transfer Entropy to Assess Interaction between Parasympathetic and Sympathetic Activities of Nervous System from HRV
Use of Mutual Information and Transfer Entropy to Assess Interaction between Parasympathetic and Sympathetic Activities of Nervous System from HRV
复制标题
利用互信息和传递熵从 HRV 评估神经系统副交感神经和交感神经活动之间的相互作用
DOI：
10.3390/e19090489
复制
发表时间：
2017-09
期刊：
影响因子：
2.7
通讯作者：
Guanzheng Liu
中科院分区：
文献类型：
--
作者：
Lianrong Zheng;Weifeng Pan;Yifang Li;Daiyi Luo;Qian Wang;Guanzheng Liu
Obstructive sleep apnea (OSA) is a common sleep disorder that often associates with reduced heart rate variability (HRV) indicating autonomic dysfunction. HRV is mainly composed of high frequency components attributed to parasympathetic activity and low frequency components attributed to sympathetic activity. Although, time domain and frequency domain features of HRV have been used to sleep studies, the complex interaction between nonlinear independent frequency components with OSA is less known. This study included 30 electrocardiogram recordings (20 OSA patient recording and 10 healthy subjects) with apnea or normal label in 1-min segment. All segments were divided into three groups: N-N group (normal segments of normal subjects), P-N group (normal segments of OSA subjects) and P-OSA group (apnea segments of OSA subjects). Frequency domain indices and interaction indices were extracted from segmented RR intervals. Frequency domain indices included nuLF, nuHF, and LF/HF ratio; interaction indices included mutual information (MI) and transfer entropy (TE (H→L) and TE (L→H)). Our results demonstrated that LF/HF ratio was significant higher in P-OSA group than N-N group and P-N group. MI was significantly larger in P-OSA group than P-N group. TE (H→L) and TE (L→H) showed a significant decrease in P-OSA group, compared to P-N group and N-N group. TE (H→L) were significantly negative correlation with LF/HF ratio in P-N group (r = −0.789, p = 0.000) and P-OSA group (r = −0.661, p = 0.002). Our results indicated that MI and TE is powerful tools to evaluate sympathovagal modulation in OSA. Moreover, sympathovagal modulation is more imbalance in OSA patients while suffering from apnea event compared to free event.
登录
查看更多内容
DOI：
10.1016/j.pnpbp.2011.03.015
发表时间：
2011-06
影响因子：
5.6
作者：
A. Voss;M. Boettger;S. Schulz;K. Gross;K. Bär
通讯作者：
A. Voss;M. Boettger;S. Schulz;K. Gross;K. Bär
DOI：
10.1007/978-3-540-36675-1_5
发表时间：
2007
期刊：
Journal of Association of Physicians of India
影响因子：
--
作者：
U. Acharya;K. Joseph;N. Kannathal;L. C. Min;Jasjit S. Suri
通讯作者：
U. Acharya;K. Joseph;N. Kannathal;L. C. Min;Jasjit S. Suri
影响因子：
2.5
作者：
Michael S Figueroa;J. Peters
通讯作者：
Michael S Figueroa;J. Peters
影响因子：
2.8
作者：
LOMBARDI, F;SANDRONE, G;MALLIANI, A
通讯作者：
MALLIANI, A
影响因子：
7.7
作者：
M. J. Lado;A. Méndez;L. R. Liñares;A. Otero;Xosé Antón Vila-Sobrino
通讯作者：
M. J. Lado;A. Méndez;L. R. Liñares;A. Otero;Xosé Antón Vila-Sobrino