Calorimetric studies on the interaction of gangliosides with phospholipids and myelin basic protein.
Calorimetric studies on the interaction of gangliosides with phospholipids and myelin basic protein.
复制标题
神经节苷脂与磷脂和髓磷脂碱性蛋白相互作用的量热研究。
DOI：
10.1016/0005-2736(84)90530-3
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
D. Bach
中科院分区：
文献类型：
--
作者：
B. Sela;D. Bach
采用差示扫描量热法研究了gm1神经节苷类与磷脂（磷脂酰乙醇胺、磷脂酰丝氨酸和磷脂酰胆碱）的相互作用。发现gm1与磷脂酰乙醇胺完全混溶；然而，与磷脂酰丝氨酸的相互作用是最小的。在gm1与磷脂酰胆碱或磷脂酰乙醇胺的相互作用产物中加入过量的Ca2+不会引起相分离。研究了髓鞘碱性蛋白对gm1热致性的影响。发现碱性蛋白对gm1胶束有很强的扰动作用。
Differential scanning calorimetry was employed to investigate the interaction of GM1gangliosides with phospholipids (phosphatidylethanolamine, phosphatidylserine or phosphatidylcholine). It was found that GM1is completely miscible with phosphatidylethanolamine; however, the interaction with phosphatidylserine is minimal. Addition of excess Ca2+to the interaction products of GM1with phosphatidylcholine or phosphatidylethanolamine did not induce phase separation. The influence of myelin basic protein on the thermotropic behaviour of GM1was also studied. It was found that basic protein has a very strong perturbing effect on GM1micelles.
牛髓磷脂碱性蛋白对鞘磷脂相变特性的影响。
DOI：
10.1016/0005-2736(82)90105-5
发表时间：
1982
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Epand,RM;Moscarello,MA
通讯作者：
Moscarello,MA