The assessment of oral health-related quality of life by factor analysis in patients with Behcet's disease and recurrent aphthous stomatitis
The assessment of oral health-related quality of life by factor analysis in patients with Behcet's disease and recurrent aphthous stomatitis
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DOI：
10.1111/j.1600-0714.2007.00514.x
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发表时间：
2007-03-01
影响因子：
3.3
通讯作者：
Direskeneli, H.
中科院分区：
文献类型：
--
作者：
Mumcu, G.;Hayran, O.;Direskeneli, H.
背景技术背景：本研究的目的是测试口腔健康影响档案-14（OHIP-14）的多维属性在白塞氏病（BD）和复发性阿弗他口炎（RAS）患者活动性oral ulcers.METHODS：96 BD患者，28例RAS患者和117名健康对照（HC）被纳入本研究。在活动性口腔溃疡患者中，记录溃疡的频率和愈合时间。结果：因子分析显示OHIP-14的3个分量表，解释了活动性口腔溃疡患者总变异的66.49%。分量表1评分与口腔溃疡月复发率呈正相关（P = 0.037）。亚量表3评分的患者与秋水仙碱治疗的患者比那些治疗与免疫抑制剂（P = 0.035）。结论：因子结构的OHIP-14被认为是可靠的，敏感的临床参数和治疗方式的活动患者。
BACKGROUND: The aim of the study was to test multidimensional properties of oral health impact profile-14 (OHIP-14) in Behcet's disease (BD) and recurrent aphthous stomatitis (RAS) patients with active oral ulcers.METHODS: Ninety-six BD patients, 28 patients with RAS and 117 healthy controls (HC) were included in this study. In patients with active oral ulcers, the frequency and healing time of ulcers were recorded. Multidimensional properties of OHIP-14 were examined by factor analysis.RESULTS: Factor analysis revealed three subscales and explained 66.49% of overall variance in these patients with active oral ulcers. The score of Subscale 1 was positively correlated with the recurrence of oral ulcers per month (P = 0.037). Subscale 3 scores of the patients treated with colchicine were worse than those treated with immunosuppressives (P = 0.035).CONCLUSIONS: The factor structure of OHIP-14 was found to be reliable and sensitive to clinical parameters and treatment modalities in active patients.