Disability in older adults: Evidence regarding significance, etiology, and risk
Disability in older adults: Evidence regarding significance, etiology, and risk
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DOI：
10.1111/j.1532-5415.1997.tb00986.x
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发表时间：
1997-01-01
影响因子：
6.3
通讯作者：
Guralnik, JM
中科院分区：
文献类型：
--
作者：
Fried, LP;Guralnik, JM
提示：本文综合和评估了目前关于身体残疾对老年人重要性的证据。然后，它认为研究结果的应用，临床老年医学practice.Results：身体残疾是一个主要的不良健康结果与老龄化。某些老年人亚组，包括行动困难、临床前功能改变和住院的人，残疾或残疾进展的风险特别高。身体残疾的主要根本原因是慢性疾病，包括急性事件，如髋骨骨折和中风，以及缓慢进展的疾病，如关节炎和心脏病。这些疾病似乎具有特定任务的影响;了解这一点可能有助于制定治疗和预防目标。科摩罗，特别是某些慢性病的组合，本身就是残疾的一个强有力的风险因素。最近的试验表明，临床干预措施可能能够防止发病或disability.CONCLUSIONS进展：现有证据表明，现在的临床方法来治疗和预防残疾和方向，为未来确定最佳的临床护理。
OBJECTIVES: This article synthesizes and assesses current evidence about the importance of physical disability to older adults. It then considers the applications of research findings to clinical geriatrics practice.RESULTS: Physical disability is a major adverse health outcome associated with aging. Certain subgroups of older adults, including individuals with mobility difficulty, with preclinical functional changes, and persons who are hospitalized, are at particularly high risk of becoming disabled or experiencing disability progression. The major underlying causes of physical disability are chronic diseases, including both acute events, such as hip fracture and stroke and slowly progressive diseases such as arthritis and heart disease. These diseases appear to have task-specific effects; understanding this may assist in setting treatment and prevention goals. Comorbidity, particularly certain combinations of chronic diseases, is a strong risk factor for disability in itself. Recent trials indicate that clinical interventions may be able to prevent onset or progression of disability.CONCLUSIONS: Available evidence now suggests clinical approaches to both treatment and prevention of disability and directions for defining optimal clinical care for the future.