Stress Responses of Neonates Related to Maternal Characteristics
Stress Responses of Neonates Related to Maternal Characteristics
复制标题
与母亲特征相关的新生儿应激反应
作者：
K. Joung;S. Cho
目的探讨婴儿足跟针刺前后的应激反应模式及相关的母亲因素。材料与方法对52例产妇及其57例婴儿进行研究。通过测量脉率、血氧饱和度和唾液皮质醇来收集新生儿的应激反应模式。收集产妇人口统计学因素和觉醒唾液。结果在不适期间，婴儿脉率中位数从132.1次/min增加到140.4次/min，唾液皮质醇从0.41 μg/dL增加到0.70 μg/dL，血氧饱和度从97%下降到95%。婴儿脉率变化与孕龄呈负相关（r =-0.37，p < 0.05），婴儿唾液皮质醇变化与母亲年龄呈正相关（r = 0.29，p < 0.05）。GA是脉率反应的唯一独立显著预测因子（R2 = 0.15，p < 0.05）。多元逐步回归分析母亲年龄对婴儿唾液皮质醇变化的影响（R2 = 0.09，p < 0.05）。结论母亲年龄和孕期是影响婴儿应激反应的重要因素。因此，重要的是要考虑母婴对的人口统计学特征，以评估这些影响因素。
Purpose To investigate the pre- and post-heelstick stress response patterns of infants and to identify related maternal factors. Materials and Methods Fifty-two mothers and their 57 infants were studied. Stress response patterns in neonates were collected by measurements of pulse rate, oxygen saturation, and salivary cortisol. Maternal demographic factors and awakening saliva were collected. Results Median level of pulse rate of infant increased from 132.1 to 140.4 beats per minute and salivary cortisol was elevated from 0.41 µg/dL to 0.70 µg/dL during the periods of discomfort, while oxygen saturation decreased from 97% to 95%. Infant's pulse rate change was negatively correlated with gestational age (GA) (r = - 0.37, p < 0.05), whereas the change of infants' salivary cortisol was correlated positively with maternal age (r = 0.29, p < 0.05). GA was the only independently significant predictor of pulse rate responses (R2 = 0.15, p < 0.05). Influence of maternal age on infants' salivary cortisol changes (R2 = 0.09, p < 0.05) was observed in a stepwise multiple regression. Conclusion These findings suggest that maternal age and gestational period can be influential factors for stress responses in infants. Therefore, it would be important to consider the demographic characteristics of mother-infant pairs to evaluate these influential factors.