A Family of Chiral Metal-Organic Frameworks
A Family of Chiral Metal-Organic Frameworks
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DOI：
10.1002/chem.201002568
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发表时间：
2011-01-01
影响因子：
4.3
通讯作者：
Kaskel, Stefan
中科院分区：
文献类型：
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作者：
Gedrich, Kristina;Heitbaum, Maja;Kaskel, Stefan
通过手性三官能团连接剂和多核锌簇的配合，得到了具有三维网状结构和大开孔（> 30埃）的手性金属有机骨架。连接体H（3）ChirBTB-n由手性恶唑烷酮取代基修饰的4，4 '，4“-苯-1，3，5-三苯甲酸酯（BTB）骨架组成。这些取代基的大小和极性决定了在溶剂热合成条件下形成的网络拓扑结构。所得的手性M0 F甚至从溶液中吸附大分子。此外，它们在Mukaiyama羟醛缩合反应中是高活性的刘易斯酸催化剂。由于它们的手性官能化，它们显示出显著水平的对映选择性，从而证明了所采用的模块化设计概念的有效性。
Chiral metal organic frameworks with a three-dimensional network structure and wide-open pores (> 30 angstrom) were obtained by using chiral trifunctional linkers and multinuclear zinc clusters. The linkers, H(3)ChirBTB-n, consist of a 4,4',4 ''-benzene-1,3,5-triyltribenzoate (BTB) backbone decorated with chiral oxazolidinone substituents. The size and polarity of these substituents determines the network topology formed under solvothermal synthesis conditions. The resulting chiral MOFs adsorb even large molecules from solution. Moreover, they are highly active Lewis acid catalysts in the Mukaiyama aldol reaction. Due to their chiral functionalization, they show significant levels of enantioselectivity, thereby proving the validity of the modular design concept employed.