Heat (shock) and the skin.
Heat (shock) and the skin.
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热（电击）和皮肤。
DOI：
10.1159/000248008
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
B. Polla,
中科院分区：
文献类型：
--
作者：
B. Polla,
尽管热疗长期以来一直用于皮肤病学治疗梅毒、淋病、牛皮癣或黑色素瘤等多种疾病，但对热休克对皮肤的生物学效应的理解吸引了对一个古老领域的新兴趣。热诱导的蛋白质（应激或热休克蛋白）似乎在保护细胞免受损伤并最终在太阳辐射的自然防御中发挥一般作用。另一方面，这些普遍存在的蛋白质也可能参与系统性红斑狼疮或麻风病等疾病的免疫病理学。
Whereas hyperthermia has long been used in dermatology for the therapy of diseases as diverse as syphilis, gonorrhea, psoriasis or melanoma, the understanding of the biological effects of heat shock on the skin attracts new interests to an old field. The proteins induced by heat (stress, or heat shock proteins) appear to play a general role in protection from cellular injury and eventually in the natural defences from solar radiation. On the other hand, these ubiquitous proteins may also be involved in the immunopathology of diseases such as systemic lupus erythematosus or leprosy.