Semi-Packed Gas Chromatography Columns With Density Modulated Pillars
Semi-Packed Gas Chromatography Columns With Density Modulated Pillars
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DOI：
10.1109/jmems.2018.2881532
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发表时间：
2019-02
影响因子：
2.7
通讯作者：
Ryan Chan;M. Agah
中科院分区：
文献类型：
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作者：
Ryan Chan;M. Agah
分离柱是影响气相色谱系统性能的重要组成部分。在众多的色谱柱设计中，微制造半填充柱在微气相色谱中引起了特别的关注，因为它比开放通道色谱柱提高了分离效率，提供了更高的样品容量。然而，这些额外的优势是以单位长度分离柱的更高压降为代价的。本文报道了一种新的半填充柱设计，通过改变柱间间距或每排柱数来调节柱的密度。制作了各种几何形状的材料，并对每排有一根或四根柱子的规则半填充柱进行了测试。测量了不同的性能指标，包括柱压降、最佳流速、理论板数和分离效率。密度调制半填充柱提供与每排嵌入更多柱的半填充柱相当的效率，同时需要较低的进口压力，这与每排嵌入一个柱的柱更具可比性。这些密度调制柱能够成功地分离柴油和煤油化合物，并确定这两种广泛使用的样品的主要碳氢化合物成分。(2018 - 0102)
The separation column is the most important component which influences the performance of gas chromatography systems. Among a number of column designs, the microfabricated semi-packed column has attracted particular attention in micro gas chromatography because it enhances the separation efficiency and provides higher sample capacity compared to the open-channel counterparts. However, these added advantages come at the cost of higher pressure drops per unit length of the separation column. This paper reports new semi-packed column designs through density modulation of the pillars by changing the spacing between rows or the number of pillars per row from. Various geometries were fabricated and tested against regular semi-packed columns having either one pillar or four pillars per row. Different performance metrics were measured including column pressure drop, optimal flow velocity, number of theoretical plates, and separation efficiency. The density-modulated semi-packed columns provide efficiencies comparable with that of semi-packed columns embedding more pillars per row while requiring a lower inlet pressure which is more comparable with the columns embedding one pillar per row. These density-modulated columns were able to successfully separate diesel and kerosene compounds and to identify the major hydrocarbon constituents of these two widely used samples. [2018-0102]