RiceGAAS: an automated annotation system and database for rice genome sequence

RiceGAAS: an automated annotation system and database for rice genome sequence
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DOI:
10.1093/nar/30.1.98
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发表时间:
2002-01-01
影响因子:
14.9
通讯作者:
Higo, K
Higo, K
中科院分区:
生物学2区
文献类型:
--
作者:
Sakata, K;Nagamura, Y;Higo, K

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国际水稻基因组测序计划(IRGSP)的广泛努力导致了基因组序列的快速积累,并且截至2001年8月,>137 Mb的基因组序列已经被提供给公共领域。这需要高通量注释方案,以定期从序列数据中提取生物学上有用且及时的信息。一个新的自动注释系统和数据库,称为水稻基因组自动注释系统(RiceGAAS)已被开发,以执行一个可靠的和最新的基因组序列的分析,以及存储和检索的注释结果。该系统具有以下功能特点:(i)从GenBank中收集水稻基因组序列;(ii)执行基因预测和同源性搜索程序;(iii)整合各种分析结果并自动解释编码区;(iv)重新执行分析、整合和自动解释参考数据库中的最新条目;(iv)重新执行分析、整合和自动解释。(v)使用基于网络的图形视图对所存储的数据进行综合可视化。RiceGAAS还有一个数据提交机制,允许公众用户对自己的序列进行全自动注释。该系统可在http://RiceGAAS.dna.affrc.go.jp/上访问。
An extensive effort of the International Rice Genome Sequencing Project (IRGSP) has resulted in rapid accumulation of genome sequence, and >137 Mb has already been made available to the public domain as of August 2001. This requires a high-throughput annotation scheme to extract biologically useful and timely information from the sequence data on a regular basis. A new automated annotation system and database called Rice Genome Automated Annotation System (RiceGAAS) has been developed to execute a reliable and up-to-date analysis of the genome sequence as well as to store and retrieve the results of annotation. The system has the following functional features: (i) collection of rice genome sequences from GenBank; (ii) execution of gene prediction and homology search programs; (iii) integration of results from various analyses and automatic interpretation of coding regions; (iv) re-execution of analysis, integration and automatic interpretation with the latest entries in reference databases; (v) integrated visualization of the stored data using web-based graphical view. RiceGAAS also has a data submission mechanism that allows public users to perform fully automated annotation of their own sequences. The system can be accessed at http://RiceGAAS.dna.affrc.go.jp/.