Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing.
Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing.
复制标题
通过聚合酶链反应检测证实慢性复发性水痘带状疱疹病毒角膜炎。
DOI：
10.1016/j.ajo.2004.12.014
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Margolis,ToddP
中科院分区：
文献类型：
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作者：
Magone,MTeresa;Nasser,RobertE;Cevallos,AVicky;Margolis,ToddP
目的报道1例儿童慢性复发性水痘病毒性角膜炎的临床表现及角膜上皮的聚合酶链反应分析。对清创假树突的分析反复为VZV DNA阳性和HSV DNA阴性。口服阿昔洛韦和外用糖皮质激素滴治疗是有效的，在消除假树突，然而，复发发生一旦药物被中止。CONCLUSIONSVaricella病毒上皮性角膜炎的儿童可以是一个经常性的慢性疾病，需要长期治疗。
PURPOSETo report a case of chronic recurrent varicella virus epithelial keratitis in a child.DESIGNCase report.METHODSClinical examination and polymerase chain reaction analysis of corneal epithelium.RESULTSA 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued.CONCLUSIONSVaricella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.