D-dimer to Rule Out Pulmonary Embolism in Renal Insufficiency
D-dimer to Rule Out Pulmonary Embolism in Renal Insufficiency
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DOI：
10.1016/j.amjmed.2013.12.003
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发表时间：
2014-04-01
影响因子：
5.9
通讯作者：
Puig, Stefan
中科院分区：
文献类型：
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作者：
Lindner, Gregor;Funk, Georg-Christian;Puig, Stefan
背景：D-二聚体水平通常在肾功能不全时升高。D-二聚体的诊断准确性，以排除肺栓塞在肾功能不全patients.METHODS：我们评估了患者的资料，提出我们的急诊科和接受计算机断层扫描血管造影，以排除肺栓塞的测量D-二聚体和肌酐。肾小球滤过率采用慢性肾脏病流行病学协作组公式计算。结果：纳入1305例患者; 1067例（82%）估计肾小球滤过率（eGFR）超过60 mL/min，209例（16%）30-60 mL/min，29例（2%）60 mL/min，30-60 mL/min为0.673。在eGFR <0.05的患者中，D-二聚体水平升高，
BACKGROUND: D-dimer levels are often elevated in renal insufficiency. The diagnostic accuracy of D-dimer to rule out pulmonary embolism in patients with renal insufficiency is unclear.METHODS: We evaluated the data of patients presenting to our Emergency Department and receiving computed tomography angiography to rule out pulmonary embolism with measurement of D-dimer and creatinine. Glomerular filtration rate was calculated using the Chronic Kidney Disease Epidemiology Collaboration formula.RESULTS: There were 1305 patients included; 1067 (82%) had an estimated glomerular filtration rate (eGFR) exceeding 60 mL/min, 209 (16%) 30-60 mL/min, and 29 (2%) 60 mL/min, and 0.673 for 30-60 mL/min.CONCLUSIONS: D-dimer levels were elevated in patients with an eGFR