Paroxetine Treatment of Problematic Pornography Use: A Case Series
Paroxetine Treatment of Problematic Pornography Use: A Case Series
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DOI：
10.1556/2006.5.2016.046
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发表时间：
2016-09-01
影响因子：
7.8
通讯作者：
Potenza, Marc N.
中科院分区：
文献类型：
--
作者：
Gola, Mateusz;Potenza, Marc N.
背景：如何最好地概念化有问题的色情内容使用（PPU）并最有效地进行干预仍然存在争议，包括强迫症（OCD）和成瘾框架。我们研究了血清素再摄取抑制剂帕罗西汀与认知行为疗法相结合治疗色情制品使用问题（PPU）的疗效。病例介绍：三名患有 PPU 的异性恋男性接受认知行为疗法和帕罗西汀治疗。在治疗期间评估色情内容的使用频率、其他性行为和焦虑。讨论：帕罗西汀治疗虽然最初似乎能有效减少色情内容的使用和焦虑，但三个月后似乎与新的强迫性性行为有关。结论：帕罗西汀可能有望短期减少 PPU 和相关焦虑，但可能会出现新的潜在令人痛苦的性行为。这些案例表明 PPU 可能来自多个领域。我们根据最近对性行为和饮酒的神经科学研究提出了对这些影响的解释。
Background: How best to conceptualize problematic pornography use (PPU) and intervene most effectively remain debated, with obsessive-compulsive disorder (OCD) and addiction frameworks. We investigated the efficacy of the serotonin-reuptake inhibitor paroxetine in combination with cognitive-behavioral therapy in the treatment of problematic pornography use (PPU). Case presentation: Three heterosexual males with PPU were treated with cognitive-behavioral therapy and paroxetine. Frequency of pornography use, other sexual behaviors, and anxiety were assessed during treatment. Discussion: Paroxetine treatment, although seemingly initially effective in reducing pornography use and anxiety, appeared related to new compulsive sexual behaviors after 3 months. Conclusions: Paroxetine may hold promise for short-term reduction of PPU and related anxiety, but new potentially distressing sexual behaviors may emerge. The cases suggest that PPU may arise from multiple domains. We propose an explanation of the effects based on recent neuroscientific research on sexual behaviors and alcohol use.