CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors
CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors
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DOI：
10.1002/stem.160387
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发表时间：
1998-01-01
期刊：
影响因子：
5.2
通讯作者：
Testa, NG
中科院分区：
文献类型：
--
作者：
de Wynter, EA;Buck, D;Testa, NG
AC133抗原是一种新的抗原，选择性地表达在人胎肝、骨髓和血液中的CD34（+）细胞亚群上，这一点已被细胞计数分析所证实。在本研究中，我们进一步评估了造血样本中CD 34（+）细胞上AC 133的表达，发现正常骨髓和脐带血与单采样本之间存在非常显著的差异（p
The AC133 antigen is a novel antigen selectively expressed on a subset of CD34(+) cells in human fetal liver, bone marrow, and blood as demonstrated by now cytometric analyses. In this study, we have further assessed the expression of AC133 on CD34(+) cells in hemopoietic samples and found that there was a highly significant difference between normal bone marrow and cord blood versus aphereses (p