Changes in Children's Sleep Duration on Food Intake, Weight, and Leptin
Changes in Children's Sleep Duration on Food Intake, Weight, and Leptin
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DOI：
10.1542/peds.2013-1274
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发表时间：
2013-12-01
期刊：
影响因子：
8
通讯作者：
Wing, Rena
中科院分区：
文献类型：
--
作者：
Hart, Chantelle N.;Carskadon, Mary A.;Wing, Rena
目的：要检查的影响，在儿童的睡眠时间的实验变化对自我报告的食物摄入量，食物强化，食欲调节激素，并测量weight.METHODS：使用内科目，平衡，交叉设计，37名儿童，8至11岁（27%超重/肥胖）完成了为期3周的研究。孩子们在家里睡了一周，然后随机增加或减少他们每晚1.5小时的床上时间，持续一周，在第三周完成交替时间表。主要结果是通过24小时饮食回忆、食物强化（即获得食物奖励的分数）和空腹瘦素和生长激素释放肽评估的饮食摄入。次要结果是儿童体重。结果：参与者在增加和减少睡眠条件之间的活动记录器定义的睡眠时间差异为2小时21分钟（P <0.001）。与睡眠减少的情况相比，在睡眠增加的情况下，儿童报告平均消耗134千卡/天（P <0.05），并表现出较低的空腹早晨瘦素值（P <0.05）。在增加睡眠期间测量的体重比减少睡眠条件下低0.22 kg（P <0.001）。在食物强化或空腹ghrelin.CONCLUSIONS：减少睡眠相比，增加睡眠时间在学龄儿童导致较低的报告食物摄入量，较低的空腹瘦素水平，体重较低。睡眠时间在儿童肥胖预防和治疗中的潜在作用值得进一步研究。
OBJECTIVE: To examine the effect of experimental changes in children's sleep duration on self-reported food intake, food reinforcement, appetite-regulating hormones, and measured weight.METHODS: Using a within-subjects, counterbalanced, crossover design, 37 children, 8 to 11 years of age (27% overweight/obese) completed a 3-week study. Children slept their typical amount at home for 1 week and were then randomized to either increase or decrease their time in bed by 1.5 hours per night for 1 week, completing the alternate schedule on the third week. Primary outcomes were dietary intake as assessed by 24-hour dietary recalls, food reinforcement (ie, points earned for a food reward), and fasting leptin and ghrelin. The secondary outcome was child weight.RESULTS: Participants achieved a 2 hour, 21 minute difference in the actigraph defined sleep period time between the increase and decrease sleep conditions (P < .001). Compared with the decrease sleep condition, during the increase condition, children reported consuming an average of 134 kcal/day less (P < .05), and exhibited lower fasting morning leptin values (P < .05). Measured weights were 0.22 kg lower during the increase sleep than the decrease sleep condition (P < .001). There were no differences in food reinforcement or in fasting ghrelin.CONCLUSIONS: Compared with decreased sleep, increased sleep duration in school-age children resulted in lower reported food intake, lower fasting leptin levels, and lower weight. The potential role of sleep duration in pediatric obesity prevention and treatment warrants further study.