Gastric carcinoma: imaging diagnosis, staging and assessment of treatment response.
Gastric carcinoma: imaging diagnosis, staging and assessment of treatment response.
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DOI：
10.1102/1470-7330.2013.0023
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发表时间：
2013-05-30
期刊：
影响因子：
--
通讯作者：
Venkatesh SK
中科院分区：
文献类型：
--
作者：
Hallinan JT;Venkatesh SK
胃癌（GC）是全球最常见的癌症相关死亡原因之一。手术切除是唯一可行的治疗方法，并且取决于胃癌的分期，包括肿瘤侵袭的深度、淋巴结的范围和远处转移。因此，准确的术前分期对于考虑术前和/或术后化疗的最佳手术管理至关重要。多探测器计算机断层扫描（MDCT）具有评估肿瘤深度、淋巴结疾病和转移的能力，是胃癌分期的首选技术。超声内镜对早期肿瘤侵壁深度的评估较为准确，但对晚期局部或狭窄性肿瘤的评估及远处转移的检测存在局限性。磁共振成像（MRI）虽然对分期有用，但尚未被证明是有效的。正电子发射断层扫描（PET）是最有用的检测和表征远处转移。MDCT和PET都有助于评估术前化疗后的治疗反应和手术切除后复发的检测。这篇综述文章讨论了成像方式在胃癌的检测、分期和治疗反应评估中的作用，以及CT体积测量、虚拟胃镜和灌注CT等新应用在胃癌治疗中的潜在作用。
Gastric carcinoma (GC) is one of the most common causes of cancer-related death worldwide. Surgical resection is the only cure available and is dependent on the GC stage at presentation, which incorporates depth of tumor invasion, extent of lymph node and distant metastases. Accurate preoperative staging is therefore essential for optimal surgical management with consideration of preoperative and/or postoperative chemotherapy. Multidetector computed tomography (MDCT) with its ability to assess tumor depth, nodal disease and metastases is the preferred technique for staging GC. Endoscopic ultrasonography is more accurate for assessing the depth of wall invasion in early cancer, but is limited in the assessment of advanced local or stenotic cancer and detection of distant metastases. Magnetic resonance imaging (MRI), although useful for staging, is not proven to be effective. Positron emission tomography (PET) is most useful for detecting and characterizing distant metastases. Both MDCT and PET are useful for assessment of treatment response following preoperative chemotherapy and for detection of recurrence after surgical resection. This review article discusses the usefulness of imaging modalities for detecting, staging and assessing treatment response for GC and the potential role of newer applications including CT volumetry, virtual gastroscopy and perfusion CT in the management of GC.
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影响因子：
2.9
作者：
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通讯作者：
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影响因子：
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作者：
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DOI：
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期刊：
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
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