Near-Infrared Light-Excited Reactive Oxygen Species Generation by Thulium Oxide Nanoparticles
Near-Infrared Light-Excited Reactive Oxygen Species Generation by Thulium Oxide Nanoparticles
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DOI：
10.1021/jacs.1c11704
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发表时间：
2022-02-16
影响因子：
15
通讯作者：
Tao, Ke
中科院分区：
文献类型：
--
作者：
Duosiken, Dida;Yang, Ruihao;Tao, Ke
探索可以吸收近红外（NIR）光以产生活性氧（ROS）的材料对于许多领域都是必要的。在这里，我们表明，氧化钍纳米粒子是可行的近红外刺激的ROS的产生。这种性质可能与Tm离子独特的能级、大的吸收截面、低的荧光发射以及类似于H-3（4）态的10（-3）s寿命有关。我们进一步证明了这些纳米颗粒对光动力疗法（PDT）的影响，其中在暴露于宽带卤素灯或808 nm激光后记录了令人印象深刻的肿瘤抑制。我们的研究结果可能会提供洞察到的领域，污染治理，精细化工合成。
Exploring materials that can absorb near-infrared (NIR) light to produce reactive oxygen species (ROS) is necessary for many fields. Herein we show that thulium oxide nanoparticles are viable for NIR-stimulated ROS generation. This property may be related to the unique energy levels, large absorption cross section, low fluorescence emission, and similar to 10(-3) s lifetime of the H-3(4) state of Tm ions. We further demonstrate the impact of these nanoparticles on photodynamic therapy (PDT), in which impressive tumor inhibition was recorded after exposure to either a broadband halogen lamp or an 808 nm laser. Our results may provide insight into the areas of photocatalysis, pollution treatment, and fine chemical synthesis.