Four novel gelsenicine-related oxindole alkaloids from the leaves of Gelsemium elegans Benth.
Four novel gelsenicine-related oxindole alkaloids from the leaves of Gelsemium elegans Benth.
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DOI：
10.1021/ol061062i
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发表时间：
2006-07-06
期刊：
影响因子：
5.2
通讯作者：
Takayama, Hiromitsu
中科院分区：
文献类型：
--
作者：
Kogure, Noriyuki;Ishii, Naoko;Takayama, Hiromitsu
[图谱]从钩吻叶中分离得到4种新类型的钩吻碱相关氧化吲哚生物碱。Gelsedilam（1）和14-acetoxygelsedilam（2）是首次发现的18，19-去甲型单萜吲哚生物碱。Gelsefuranidine（3）和gelseiridone（4）分别在gelsenicine相关的单萜吲哚生物碱上具有额外的呋喃残基或环烯醚萜单元。
[GRAPHICS]New types of four gelsenicine-related oxindole alkaloids were isolated from the leaves of Gelsemium elegans Benth. Gelsedilam (1) and 14-acetoxygelsedilam (2) are the first examples of 18,19-nor-type monoterpenoid indole alkaloids. Gelsefuranidine (3) and gelseiridone (4) have, respectively, an additional furan residue or an iridoid unit on the gelsenicine-related monoterpenoid indole alkaloid.