How methionine and glutamine prevent inhibition of growth by methionine sulfoximine.
How methionine and glutamine prevent inhibition of growth by methionine sulfoximine.
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DOI:
10.1016/0005-2736(72)90146-0
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发表时间:
1972-04
期刊:
影响因子:
--
通讯作者:
F. Meins;Marc L. Abrams
中科院分区:
文献类型:
--
作者:
F. Meins;Marc L. Abrams
Methionine sulfoximine, a potent inhibitor of glutamine synthetase, inhibits growth ofChlorella vulgaris. Growth inhibition is prevented by adding L-glutamine or L-methionine to the growth medium. We show that glutamine and methionine act by blocking methionine sulfoximine uptake into the cell.