2′-O-alkyloligoribonucleotides Synthesis and Applications in Studying RNA Splicing
2′-O-alkyloligoribonucleotides Synthesis and Applications in Studying RNA Splicing
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2′-O-烷基寡核糖核苷酸的合成及其在RNA剪接研究中的应用
DOI：
10.1080/07328319108046433
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
A. Lamond
中科院分区：
文献类型：
--
作者：
B. Sproat;A. Iribarren;B. Beijer;U. Pieles;A. Lamond
摘要改进了2′-O-烯丙基核糖核苷-3 ′-O-亚磷酰胺的合成路线。2′-O-烯丙基寡核糖核苷酸被证明是研究RNA加工的上级反义化合物。
Abstract Improved synthetic routes have been established for the preparation of appropriately protected 2′-O-allylribonucleoside-3′-O-phosphoramidites. 2′-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.