Pesticide exposure of children in an agricultural community: Evidence of household proximity to farmland and take home exposure pathways
Pesticide exposure of children in an agricultural community: Evidence of household proximity to farmland and take home exposure pathways
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DOI：
10.1006/enrs.2000.4076
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发表时间：
2000-11-01
影响因子：
8.3
通讯作者：
Kalman, D
中科院分区：
文献类型：
--
作者：
Lu, CS;Fenske, RA;Kalman, D
在华盛顿州中部的一个农业社区，对儿童接触有机磷（OP）农药进行了测定。从109名9个月至6岁的儿童中收集了现场尿液和手擦拭样本，以及房屋灰尘样本和各种表面的擦拭样本。根据父母的职业（农业与非农业）和家庭与农药处理果园的接近程度对儿童进行分类。在农业家庭的家中，二甲基OP农药的中位屋尘浓度是参考家庭的7倍（1.92 vs 0.27 pg/g; P< 0.001）。农业儿童的农药代谢物浓度中位数是参考儿童的5倍（0.05 vs 0.01 g/ml; P=0.09）。中位农药浓度在室内灰尘（P=0.01）和代谢物浓度在尿液中（P=0.01）从农业家庭显着较高的儿童生活在附近的处理果园（在200英尺或60米）比那些生活更远。61名农业儿童中有10名手上有可检测到的OP农药，而参考儿童中没有一名有可检测到的水平。这些研究结果表明，与使用农药的父母一起生活的儿童，或生活在农药处理过的农田附近的儿童，比生活在同一社区的其他儿童有更高的暴露（C）2000年学术出版社。
Children's exposure to organophosphorus (OP) pesticides in an agricultural community in central Washington State was determined. Spot urine and hand wipe samples were collected from 109 children 9 months to 6 years of age, as were house dust samples, and wipe samples from various surfaces. Children were categorized based on parental occupation (agricultural vs nonagricultural) and on household proximity to pesticide-treated orchards. Median house dust concentrations of dimethyl OP pesticides in homes of agricultural families were seven times higher than those of reference families (1.92 vs 0.27 pg/g; P< 0.001). Median pesticide metabolite concentrations in agricultural children were five times higher than those in reference children (0.05 vs 0.01 g/ml; P=0.09). Median pesticide concentrations in housedust (P=0.01) and metabolite concentrations in urine (P=0.01) from agricultural families were significantly higher in the children living near treated orchards (within 200 ft or 60 m) than those living more distant. Ten of 61 agricultural children had detectable OP pesticide levies on their hands, whereas none of the reference children had detectable levels. These findings indicate that children living with parents who work with agricultural pesticides, or who live in proximity to pesticide-treated farmland, have higher exposures than do other children living in the same community (C) 2000 Academic Press.