A Time-Variant Processing Approach for the Analysis of Alpha and Gamma MEG Oscillations During Flicker Stimulus Generated Entrainment
A Time-Variant Processing Approach for the Analysis of Alpha and Gamma MEG Oscillations During Flicker Stimulus Generated Entrainment
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一种时变处理方法，用于分析闪烁刺激产生的夹带期间的 Alpha 和 Gamma MEG 振荡
DOI：
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发表时间：
2011
影响因子：
4.6
通讯作者：
H. Witte
中科院分区：
文献类型：
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作者：
M. Wacker;M. Galicki;P. Putsche;T. Milde;K. Schwab;J. Haueisen;C. Ligges;H. Witte
重复闪烁刺激（光驱动）提供了通过MEG/EEG分析来研究刺激敏感的神经元振荡器的性质和耦合特性的可能性。与闪烁频率的区域中的个别α带频率，动力学的夹带过程的α振荡，以及伴随的γ振荡和振荡之间的耦合的动力学，通过适当的组合的时变分析方法的装置进行了研究。Hilbert和Gabor变换揭示了在整个频率范围内夹带过程的时变特性（频率夹带、相位锁定和n：m同步）。此外，应用时变部分定向相干性来识别眼扫视干扰，并研究在夹带期间同时导出的MEG/EEG数据的记录位点之间的定向信息传递。MEG数据是本方法研究的重点，因为MEG中α振荡的夹带效应比EEG中更强。主要研究了枕叶脑区（视觉皮层），并量化了α夹带的动力学。它可以表明，在这个夹带的开始，一个瞬态的，强烈的锁相“40赫兹”的伽马振荡发生。
Repetitive flicker stimulation (photic driving) offers the possibility to study the properties and coupling characteristics of stimulation-sensitive neuronal oscillators by means of the MEG/EEG analysis. With flicker frequencies in the region of the individual alpha band frequency, the dynamics of the entrainment process of the alpha oscillation, as well as the dynamics of the accompanying gamma oscillations and the coupling between the oscillations, are investigated by means of an appropriate combination of time-variant analysis methods. The Hilbert and the Gabor transformation reveal time-variant properties (frequency entrainment, phase locking, and n:m synchronization) of the entrainment process in the whole frequency range. Additionally, time-variant partial directed coherence is applied to identify ocular saccadic interferences and to study the directed information transfer between the recording sites of the simultaneously derived MEG/EEG data during the entrainment. The MEG data is the focus of this methodological study as the entrainment effects of the alpha oscillation are stronger in MEG than in the EEG. The occipital brain region (visual cortex) was mainly investigated and the dynamics of the alpha entrainment quantified. It can be shown that at the beginning of this entrainment, a transient, strongly phase-locked “40-Hz” gamma oscillation occurs.