The influences of stenosis on the downstream flow pattern in curved arteries
The influences of stenosis on the downstream flow pattern in curved arteries
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DOI：
10.1016/j.medengphy.2006.09.009
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发表时间：
2007-10-01
影响因子：
2.2
通讯作者：
Liu, Biyue
中科院分区：
文献类型：
--
作者：
Liu, Biyue
本文通过计算机模拟研究了狭窄对弯曲动脉内脉动血流模式的影响。采用不同的生理参数值进行数值计算，以检查狭窄对血流动力学特性（如二次流、流动分离、壁面切应力（WSS）和压降）的影响。结果表明，当弯曲动脉的内壁处的狭窄程度达到一定程度时，与没有狭窄的弯曲动脉相比，动脉下游的流动模式显示出显著的变化。根据先前的研究，在弯曲的动脉中，在弯曲的内壁处发生流动分离。本工作报告的分析，这样的流动分离面积在内壁的狭窄后区域在弯曲的动脉狭窄。此外，另一个区域的流动分离与低和振荡的WSS和血压的外壁在下游管也被发现和研究。观察到的下游流动的特征变化可能表明在下游外壁处形成了新的斑块。(c)2006年IPEM。由爱思唯尔有限公司出版。保留所有权利。
The influence of stenosis on the pulsatile blood flow pattern in curved arteries with stenosis at inner wall was investigated by computer simulations. Numerical calculations were performed with various values of physiological parameters to examine the effect of a stenosis on the hemodynamic characteristics such as secondary flow, flow separation, wall shear stress (WSS) and pressure drop. The results demonstrated that when the severity of a stenosis at the inner wall of a curved artery reaches a certain level, the flow pattern in the downstream of the artery shows a dramatic change compared to that of a curved artery with no stenosis. According to previous studies, a flow separation occurs at the inner wall of the bend in a curved artery. The present work reports an analysis of such a flow separation area at the inner wall of the post stenosis region in curved arteries with a stenosis. In addition, another area of flow separation with low and oscillating WSS and blood pressure at the outer wall in a downstream tube was also found and investigated. The observed characteristic change of the flow downstream may suggest a formation of a new plaque at the outer wall downstream. (c) 2006 IPEM. Published by Elsevier Ltd. All rights reserved.