Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff

Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
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DOI:
10.1016/j.jhin.2020.06.028
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发表时间:
2020-09-01
影响因子:
6.9
通讯作者:
Vandenberg, O.
Vandenberg, O.
中科院分区:
医学3区
文献类型:
--
作者:
Martin, C.;Montesinos, I;Vandenberg, O.

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在2019年冠状病毒病高度暴露单位工作的工作人员被邀请参加为期6个月的严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)携带和血清阳性率研究。第1天和第15天的访视结果显示,在326名参与者中,通过逆转录聚合酶链反应和/或血清学确认了41例SARS-CoV-2感染(总感染率为12.6%)。样本采集时存在合并症或症状是感染的风险因素,但作为医生/护士工作不是风险因素。在高风险单位进行的普遍筛查,无论症状如何,都可以发现无症状和可能具有传染性的受感染工人,使他们能够自我隔离7天。(C)2020年,卫生保健感染协会。由爱思唯尔有限公司出版。保留所有权利。
Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days. (C) 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.