THE DEFINITION OF HEART-FAILURE

THE DEFINITION OF HEART-FAILURE
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DOI:
10.1093/oxfordjournals.eurheartj.a061500
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发表时间:
1983-01-01
影响因子:
39.3
通讯作者:
REALE, A
REALE, A
中科院分区:
医学1区
文献类型:
--
作者:
DENOLIN, H;KUHN, H;REALE, A

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虽然每个人都认为他们知道心力衰竭意味着什么,但没有普遍接受的定义。下面的观点和定义描述了这种矛盾的情况:“很明显,心力衰竭的诊断,就像许多其他疾病一样,取决于它的定义,这取决于不同的权威机构”!1]。“由于没有单一的测量方法可以区分正常和衰竭的心脏,因此没有普遍接受的心力衰竭定义!二!“我们还没有等待一个可靠的和可重复的测试,将告诉我们,如果一个心脏是好还是坏!”3)。迄今为止,几乎所有关于充血性心力衰竭的研究都因缺乏一致的诊断标准和全面的随访评估而受到阻碍。“目前,心力衰竭可以定义为心肌功能异常导致心脏无法泵血以满足代谢组织需求的病理状态!5)。心力衰竭是一种病理生理状态,在这种状态下,心脏功能异常导致心脏不能以正常的速度泵血,从而导致代谢产物的产生。L.“心力衰竭是一种异常状况,其中心脏功能紊乱是心脏无法以与全身代谢需求相称的速率泵血的主要原因”t7)。在实践中,心力衰竭最好用两种主要的临床表现来描述,即肺充血和外周灌注不足。心力衰竭(Herzinsuffizienz)是指心输出量不足;即在休息或运动时,尽管心输出量正常(即无心力衰竭),但可能存在异常心肌功能(例如心室充盈压和/或舒张末期心室容积异常增加)!九!
Although everybody feels they know what heart failure means, there is no generally accepted definition. The following opinions and definitions describe the conflicting situation:'It should be obvious that the diagnosis of cardiac failure, like that of many other diseases, depends upon its definition, which varies with different authorities'! 1].'Since no single measurement discriminates between the normal and failing heart, no definition of heart failure is universally accepted! 2!.'We have yet to wait for a reliable and reproducible test that will tell us if a heart is good or bad'! 3).'To date virtually all studies of congestive heart failure have been hampered by the lack of consistent diagnostic criteria and comprehensive follow-up evaluation'M.'For the present, heart failure may be defined as the pathologic condition in which an abnormality of cardiac muscle function is responsible for the inability of the heart to pump blood at a level adequate to meet metabolic tissue demands! 5).'Heart failure is the pathophysiologic state in which an abnormality 01 cardiac function is responsible forfhe failure of the heart to pump blood at a rale rpTrnmsiiratf W'7K th<* p* q"'f*-ments of the metabpiiyinft t)'ssnes3? l.'Heart failure is the abnormal condition in which disturbed cardiac performance is primarily responsible for the inability of the heart to pump blood at a rate commensurate with systemic metabolic requirements' t7).'In practice, heart failure is best described in terms of its two primary sets of clinical manifestations, pulmonary congestion and peripheral hypoperfusionW.'Cardiac failure (Herzinsuffizienz) means insufficient cardiac output; ie at rest or at exercise abnormal myocardial function (eg abnormal increase of ventricular filling pressure and/or of end-diastolic ventricular volume) may be present in spite of normal cardiac output (ie without cardiac failure)! 9!.