Sclerotherapy for the mucoceles of the anterior lingual salivary glands with pingyangmycin.
Sclerotherapy for the mucoceles of the anterior lingual salivary glands with pingyangmycin.
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DOI：
10.1111/odi.12155
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发表时间：
2014-07
期刊：
影响因子：
3.8
通讯作者：
Y. Cai;R. Wang;S-F Yang;Y. Zhao;J-H Zhao
中科院分区：
文献类型：
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作者：
Y. Cai;R. Wang;S-F Yang;Y. Zhao;J-H Zhao
由于舌前涎腺(ALSG)的解剖特点，如果采用手术治疗，其复发是非常常见的。因此，迫切需要应用更有效、侵入性更小的治疗方法来取代手术。在本研究中，40例ALSGs粘液囊肿患者接受了平阳霉素的瘤内注射，平均每例患者注射次数为2.075次(范围1-3次)。术后随访16个月以上，全部痊愈，无复发。并发症包括注射后局部肿胀、疼痛和溃疡，所有这些症状在注射后7-10天消失。综上所述，平阳霉素硬化疗法是治疗ALSGs粘液囊肿的一种有效、安全的方法，可能是主要的治疗手段。
Recurrence is very common if the mucoceles of the anterior lingual salivary glands (ALSGs) are treated by surgery due to its anatomic characteristics. Therefore, more effective and less invasive treatment methods are urgently required to be applied instead of surgery. In this study, 40 patients with the mucocele of the ALSGs received the intralesional injections of pingyangmycin, and the median number of injections per patient was 2.075 (range, 1-3). All cases completely recovered with no recurrence after follow-up of more than 16 months. The complications included the local swelling, pain, and ulceration following injection, and all these symptoms resolved 7-10 days after the injection. Taken together, sclerotherapy with pingyangmycin is an effective and safe treatment method for the mucocele of the ALSGs and may be the primary treatment modality.