The tuberculin skin test.

The tuberculin skin test.
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DOI:
10.1164/arrd.1972.105.5.855a
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发表时间:
1972-05
期刊:
The American review of respiratory disease
影响因子:
--
通讯作者:
D. T. Carr
D. T. Carr
中科院分区:
其他
文献类型:
--
作者:
D. T. Carr

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维斯瓦纳坦及其同伙!在综述中报道,在28只猴子中,有7只在旋转鼓中呼吸氧气浓度约为10%的空气时发生了高海拔肺水肿。10只松鼠猴在低压舱中暴露于16,500英尺(404 mm Hg)的模拟高度55天。在实验的前三天,猴子被迫在一个深槽中游泳,直到耗尽,其中氧气含量为11%。当动物筋疲力尽时,它们会呕吐,然后下沉。当猴子从水里被救出来并仰面躺下时,没有一只猴子能站起来。运动期结束后,立即用毛巾擦干猴子并将其送回低压舱。需要每天短时间暴露于海平面压力下拍摄胸片。在暴露于404毫米汞柱下55天后,猴子们被恢复到海平面压力
Viswanathan and associates! reported in the REVIEW the occurrence of high altitude pulmonary edema in 7 of 28 monkeys placed in a revolving drum while breathing an atmosphere with an oxygen concentration of approximately 10 per cent. Attempts in this laboratory to induce pulmonary edema in squirrel monkeys have been unsuccessful. Ten squirrel monkeys were exposed to a simulated altitude of 16,500 feet (404 mm Hg) in a hypobaric chamber for 55 days. During the first 3 days of the experiment, the monkeys were forced to swim until exhausted in a deep tank in an 11 per cent oxygen atmosphere. When the animals were exhausted, they would vomit and then sink. When retrieved from the water and laid on their backs, none of the monkeys could right themselves. Immediately after the exercise period, the monkeys were towel-dried and returned to the hypobaric chamber. Brief daily periods of exposure to sea level pressure were required to take chest films. After 55 days of exposure to 404 mm Hg, the monkeys were returned to sea level pressure