BEHAVIORAL AND BIOLOGIC ASPECTS OF MARIJUANA USE *
BEHAVIORAL AND BIOLOGIC ASPECTS OF MARIJUANA USE *
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大麻使用的行为和生物学方面*
DOI：
10.1111/j.1749-6632.1976.tb49899.x
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发表时间：
1976
影响因子：
5.2
通讯作者：
Issac Greenberg
中科院分区：
文献类型：
--
作者：
J. Mendelson;T. Babor;J. Kuehnle;A. Rossi;J. Bernstein;N. Mello;Issac Greenberg
在本十年之前，仅进行了三项关于重复剂量大麻管理影响的综合研究。zs45,52我们目前的数据库已大大扩展，并已在几家综合出版物中进行了部分审查z53然而，尽管我们关于大麻对人类生物功能和行为影响的信息基金呈指数增长，但我们仍然无法确定可能与长期大麻相关的任何微妙甚至灾难性后果的类型和性质使用。本文提供的数据转载了我们实验室进行的一系列多学科研究的概述。我们在这项研究中解决的主要问题与我们在之前提出的问题类似。这些问题是：“长期吸食大麻是否会系统性地影响参与各种社会和目标导向活动的动机？自由选择大麻摄入量与之前和随后的情绪状态之间是否存在恒定的关系？自由选择大麻摄入量与言语互动模式之间有什么关系？自由选择大麻摄入量与心理表现之间有什么关系？”评估问题解决和冒险、记忆、时间估计和认知功能等功能的任务？最后，生理和生化变化是否与重复服用大麻有关？”本手稿的每个主题部分都提供了这些问题的一些答案。本报告总结了我们实验室和临床研究机构正在进行的研究的当前“科学状况”。 Babor 博士及其同事将发表关于行为和社会反应、群体互动和耐受性研究中获得的数据的更详细介绍。 A. Michael Rossi 博士和他的同事将在随后的出版物中报告有关情绪、短期记忆、警惕性和反应时间的研究。博士。 Kuehnle 和 Bernstein 已提交有关精神病学方面以及心肺功能的数据以供发表。博士。格林伯格和梅洛及其同事在本专着的其他地方详细描述了操作行为的研究。我们要强调的最重要的关节之一是 35、37。
Before the current decade, only three comprehensive studies of the effects of repeat-dose marijuana administration had been conducted.zs45,52 Our current data base has been expanded considerably and has been reviewed in part in several comprehensive publicatiorsz53 Yet, despite an exponential increment in our fund of information about the effects of marijuana on human biologic function and behavior, we are still far from certain about the type and nature of any subtle, and perhaps disastrous, consequences that may be associated with long-term marijuana use. Data presented in this paper reprint an overview of a series of multidisciplinary studies conducted in our laboratory. The major questions that we addressed in this research were similar to those we have posed in previous These questions were: “Does chronic use of marijuana systematically affect motivation to engage in a variety of social and goal-directed activities? Are there constant relationships between free-choice marijuana intake and antecedent and consequent mood states? What are the relationships between free-choice marijuana intake and patterns of verbal interaction? What are the relationships between free-choice marijuana intake and performance on psychologic tasks that assess such functions as problem solving and risk taking, memory, time estimation, and cognitive function? And, finally, are physiologic and biochemical changes associated with repeated doses of marijuana?” Some answers for these questions are provided in each of the topical sections of this manuscript. This report is a summary of the current “state of science” for ongoing research in our laboratory and clinical research facility. More detailed presentations of data obtained in studies of behavorial and social reactions, group interaction, and tolerance will be published by Dr. Babor and his associates. Dr. A. Michael Rossi and his colleagues will report in subsequent publications on studies of mood, short-term memory, vigilance, and reaction time. Drs. Kuehnle and Bernstein have submitted data for publication on psychiatric aspects and cardiac and pulmonary function. Drs. Greenberg and Mello and their associates have presented a detailed description of studies of operant behavior elsewhere in this monograph. One of the most important joints we would like to emphasize is the 35, 37.