Infants born to mothers with severe acute respiratory syndrome
Infants born to mothers with severe acute respiratory syndrome
复制标题
DOI：
10.1542/peds.112.4.e254
复制
发表时间：
2003-10-01
期刊：
影响因子：
8
通讯作者：
Fok, TF
中科院分区：
文献类型：
--
作者：
Shek, CC;Ng, PC;Fok, TF
严重急性呼吸系统综合症（SARS）是一种新发现的由新型冠状病毒引起的传染病。香港社区爆发期间，感染SARS的孕妇产下了5名活产婴儿。对 SARS 相关冠状病毒围产期传播的系统研究，包括系列逆转录酶聚合酶链反应测定、病毒培养和配对血清滴度，均未能在任何婴儿中检测到病毒。此外，所有婴儿均未出现提示 SARS 的临床、放射学、血液学或生化证据。一名早产儿出现空肠穿孔，另一名早产儿在出生后不久出现坏死性小肠结肠炎伴回肠穿孔。本病例系列是第一份描述 SARS 孕妇所生第一批活产婴儿临床病程的报告。
Severe acute respiratory syndrome (SARS) is a newly discovered infectious disease caused by a novel coronavirus. During the community outbreak in Hong Kong, 5 liveborn infants were born to pregnant women with SARS. A systematic search for perinatal transmission of the SARS-associated coronavirus, including serial reverse transcriptase-polymerase chain reaction assays, viral cultures, and paired serologic titers, failed to detect the virus in any of the infants. In addition, none of the infants developed clinical, radiologic, hematologic, or biochemical evidence suggestive of SARS. One preterm infant developed jejunal perforation and another developed necrotizing enterocolitis with ileal perforation shortly after birth. This case series is the first report to describe the clinical course of the first cohort of liveborn infants born to pregnant women with SARS.