Chromosome inversions and ecological plasticity in the main African malaria mosquitoes.
Chromosome inversions and ecological plasticity in the main African malaria mosquitoes.
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DOI：
10.1111/evo.13176
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发表时间：
2017-03
期刊：
影响因子：
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通讯作者：
Fontenille D
中科院分区：
文献类型：
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作者：
Ayala D;Acevedo P;Pombi M;Dia I;Boccolini D;Costantini C;Simard F;Fontenille D
染色体倒位一直吸引着科学界，主要是因为它们在不同分类群快速适应不断变化的环境中所起的作用。然而，与染色体倒位相关的生态性状研究甚少。在这里，我们研究了23个染色体倒位在非洲四种主要的非洲疟疾蚊子对当地环境的适应中所起的作用。我们利用空间显式模型研究了它们的分布格局，并对每个反演范围的生态地理决定因素进行了表征。然后，我们进行了层次聚类和约束排序分析，以评估反转之间的空间和生态相似性。我们的研究结果表明，大多数倒序是环境结构的，表明它们积极参与了局部适应过程。4种蚊种间的地理格局和生态需求在某些倒转过程中表现出相似，为平行进化提供了证据。相反，兄弟物种之间常见的反转多态性表现出不同的生态模式，这表明它们可能在每个物种中具有不同的适应作用。这些结果与染色体倒位在按蚊生态适应中起作用的发现是一致的。该研究为未来基于基因组的分析奠定了强大的生态学基础，以阐明这四种蚊子的本地适应遗传机制。
Chromosome inversions have fascinated the scientific community, mainly because of their role in the rapid adaption of different taxa to changing environments. However, the ecological traits linked to chromosome inversions have been poorly studied. Here, we investigated the roles played by 23 chromosome inversions in the adaptation of the four major African malaria mosquitoes to local environments in Africa. We studied their distribution patterns by using spatially explicit modeling and characterized the ecogeographical determinants of each inversion range. We then performed hierarchical clustering and constrained ordination analyses to assess the spatial and ecological similarities among inversions. Our results show that most inversions are environmentally structured, suggesting that they are actively involved in processes of local adaptation. Some inversions exhibited similar geographical patterns and ecological requirements among the four mosquito species, providing evidence for parallel evolution. Conversely, common inversion polymorphisms between sibling species displayed divergent ecological patterns, suggesting that they might have a different adaptive role in each species. These results are in agreement with the finding that chromosomal inversions play a role in Anopheles ecotypic adaptation. This study establishes a strong ecological basis for future genome-based analyses to elucidate the genetic mechanisms of local adaptation in these four mosquitoes.