Socially induced sex change regulates forebrain isotocin in Lythrypnus dalli
Socially induced sex change regulates forebrain isotocin in Lythrypnus dalli
复制标题
DOI：
10.1097/00001756-200401190-00036
复制
发表时间：
2004-01-19
期刊：
影响因子：
1.7
通讯作者：
Grober, MS
中科院分区：
文献类型：
--
作者：
Black, MP;Reavis, RH;Grober, MS
神经垂体肽在进化上是保守的，并且它们的表达可以受到社会调节。我们的问题是，社会引起的性别变化会对前脑异产素（一种催产素同系物）产生什么影响？我们将雄性从社会群体中剔除，以诱导占主导地位的雌性改变性别，并在Lythrypnus dalli中变成雄性。性别改变后期的鱼类比早期和未改变性别的雌性具有更少的前脑同产素免疫反应（-ir）细胞。当群体被合并为明确的雄性（对照雄性和变性的新雄性）和明确的雌性（在作为雄性求爱之前的鱼）时，雌性比对照雄性和最近变性的鱼拥有更多的等产素细胞。这是第一项证明前脑异产素的社会调节作用的研究。
The neurohypophyseal peptides are evolutionarily conserved and their expression can be socially modulated. Our question was what effect will socially induced sex change have on forebrain isotocin, an oxytocin homologue? We removed males from social groups to induce dominant females to change sex and become males in Lythrypnus dalli. Fish in the late stages of sex change had fewer forebrain isotocin-immunoreactive (-ir) cells than early stage and unchanged females. When groups were consolidated into unequivocal males (control males and sex-changed new males) and unequivocal females (fish prior to courtship as a male), females had significantly more isotocin-ir cells than control males and recently sex-changed fish. This is the first study demonstrating the social regulation of forebrain isotocin.