A histochemical study of the fibrinolytic activity. Cornea, conjunctiva, and lacrimal gland.

A histochemical study of the fibrinolytic activity. Cornea, conjunctiva, and lacrimal gland.
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纤溶活性的组织化学研究。

DOI:
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发表时间:
1967
期刊:
A M A Archives of Ophthalmology
影响因子:
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通讯作者:
T. Astrup
T. Astrup
中科院分区:
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文献类型:
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作者:
M. Pandolfi;T. Astrup

文献摘要

被引文献

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通过组织化学纤维蛋白玻片技术研究,人和几种哺乳动物的正常角膜切片无纤维蛋白溶解活性。角膜损伤后,纤溶酶原激活物可与上皮或内皮衬里以及脱落的上皮或内皮细胞相关。一般而言,严重退化的细胞显示最高的纤溶活性。在角膜上皮碎片中,可以证明弱蛋白酶效应。纤溶酶原激活剂的可能来源及其可能的生理功能进行了讨论。
Studied by the histochemical fibrin slide technique sections of normal cornea of man and several mammals are fibrinolytically inactive. After corneal injury plasminogen activator can be demonstrated in relation to the epithelial or endothelial linings and in detached epithelial or endothelial cells. In general, severely degenerated cells show the highest fibrinolytic activity. In fragments of corneal epithelium a weak protease effect could be demonstrated. The possible origin of the plasminogen activator and its possible physiological functions are discussed.