Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures
Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures
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DOI：
10.1093/carcin/17.8.1633
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发表时间：
1996-08-01
期刊：
影响因子：
4.7
通讯作者：
Wright, EG
中科院分区：
文献类型：
--
作者：
Clutton, SM;Townsend, KMS;Wright, EG
There is accumulating evidence that cells exposed to low and often environmentally relevant doses of ionizing radiation survive the initial insult, but transmit genomic instability to their progeny. The underlying mechanism of radiation-induced genomic instability is unknown, We present biochemical evidence consistent with the hypothesis that enhanced and persistent oxy-radical activity may be responsible.
