Microscale tipstreaming in a microfluidic flow focusing device
Microscale tipstreaming in a microfluidic flow focusing device
复制标题
DOI：
10.1063/1.2397023
复制
发表时间：
2006-12-01
影响因子：
4.6
通讯作者：
Mayer, Hans C.
中科院分区：
文献类型：
--
作者：
Anna, Shelley L.;Mayer, Hans C.
利用微流控流动聚焦装置，探索了利用表面活性剂介导的尖端流合成微米级和更小的液滴。通过控制可溶性非离子表面活性剂的表面活性剂本体浓度在临界胶束浓度附近，沿着随着毛细管数和内部和外部流速的比率，我们观察到几种不同的液滴破碎模式。在大多数情况下，微流体装置中的液滴破碎导致尺寸在数十微米范围内的高度单分散液滴。然而，我们观察到一种新的分裂模式，称为“螺纹形成”，类似于尖端流，并产生几微米或更小的微小液滴。在这项工作中，我们的特征的线程的增长和其最大长度作为一个函数的流量变量和表面活性剂含量，我们还表征了这些变量的函数的液滴破裂的时期。我们的研究结果提出了控制这一过程的可能方法。使用一个简单的流动可视化实验的基础上，我们报告的初步努力，模拟螺纹形成过程。(c)2006年，美国物理学会。
A microfluidic flow-focusing device is used to explore the use of surfactant-mediated tipstreaming to synthesize micrometer-scale and smaller droplets. By controlling the surfactant bulk concentration of a soluble nonionic surfactant in the neighborhood of the critical micelle concentration, along with the capillary number and the ratio of the internal and external flow rates, we observe several distinct modes of droplet breakup. For the most part, droplet breakup in microfluidic devices results in highly monodisperse droplets in the range of tens of micrometers in size. However, we observe a new mode of breakup called "thread formation" that resembles tipstreaming and yields tiny droplets in the range of a few micrometers in size or smaller. In this work, we characterize the growth of the thread and its maximum length as a function of flow variables and surfactant content, and we also characterize the period of droplet breakup as a function of these variables. Our results suggest possible methods for controlling the process. Using a simple flow visualization experiment as the basis, we report on preliminary efforts to model the thread formation process. (c) 2006 American Institute of Physics.