One-pot oxidative Mannich-type reaction of lactams with alkyl malonates
One-pot oxidative Mannich-type reaction of lactams with alkyl malonates
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DOI：
10.1016/j.tetlet.2007.03.025
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发表时间：
2007-04-30
影响因子：
1.8
通讯作者：
Ishibashi, Hiroyuki
中科院分区：
文献类型：
--
作者：
Matsuo, Jun-ichi;Tanaki, Yumi;Ishibashi, Hiroyuki
一锅取代的C-H键的位置旁边的氮原子的内酰胺与烷基丙二酸酯进行有效的脱氢的内酰胺与N-叔丁基苯亚磺酰亚胺酰氯，然后由曼尼希型加成的烷基丙二酸酯。(c)2007爱思唯尔有限公司保留所有权利。
One-pot substitution of a C-H bond at the position next to the nitrogen atom of lactams with alkyl malonates proceeded effectively by dehydrogenation of lactams with N-tert-butylbenzenesulfinimidoyl chloride, followed by Mannich-type addition of alkyl malonates. (c) 2007 Elsevier Ltd. All rights reserved.