Six-year results of a prospective study of metal ion levels in young patients with metal-on-metal hip resurfacings
Six-year results of a prospective study of metal ion levels in young patients with metal-on-metal hip resurfacings
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DOI：
10.1302/0301-620x.91b2.21654
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发表时间：
2009-02-01
影响因子：
--
通讯作者：
McMinn, D. J. W.
中科院分区：
文献类型：
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作者：
Daniel, J.;Ziaee, H.;McMinn, D. J. W.
我们描述了一项正在进行的前瞻性临床放射学和金属离子研究的结果，该研究在26名连续男性患者中进行，这些患者接受了单侧伯明翰髋关节表面置换术，其中有两种股骨头尺寸（50 mm和54 mm）。他们的平均年龄为52.9岁（29至67岁）。我们以前已经表明，早期增加的24小时尿排泄的金属离子，达到高峰，在6个月（钴）和一年（铬）后的操作。随后，钴和铬的排泄量呈下降趋势。全血中的钴和铬水平在一年内也显示出显着增加，随后呈下降趋势，直到第六年。
We describe the findings at six years in an ongoing prospective clinicoradiological and metal ion study in a cohort of 26 consecutive male patients with unilateral Birmingham Hip Resurfacing arthroplasties with one of two femoral head sizes (50 mm and 54 mm). Their mean age was 52.9 years (29 to 67). We have previously shown an early increase in the 24-hour urinary excretion of metal ions, reaching a peak at six months (cobalt) and one year (chromium) after operation. Subsequently there is a decreasing trend in excretion of both cobalt and chromium. The levels of cobalt and chromium in whole blood also show a significant increase at one year, followed by a decreasing trend until the sixth year.