Structure elucidation of fungal beauveriolide III, a novel inhibitor of lipid droplet formation in mouse macrophages
Structure elucidation of fungal beauveriolide III, a novel inhibitor of lipid droplet formation in mouse macrophages
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DOI：
10.7164/antibiotics.52.7
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发表时间：
1999-01-01
影响因子：
3.3
通讯作者：
Omura, S
中科院分区：
文献类型：
--
作者：
Namatame, I;Tomoda, H;Omura, S
通过光谱分析和化学降解，真菌白僵菌内酯 III 是小鼠巨噬细胞中脂滴形成的抑制剂，其结构被阐明为环-[(3S,4S)-3-羟基-4-甲基辛酰基-L苯丙氨酰-L-丙氨酰-D-别异亮氨酰]。
The structure of fungal beauveriolide III, an inhibitor of lipid droplet formation in mouse macrophages, was elucidated to be cyclo-[(3S,4S)-3-hydroxy-4-methyloctanoyl-Lphenylalanyl-L-alanyl-D-allo-isoleucyl] by spectral analyses and chemical degradation.