Usefulness of the mayo adhesive probability score as a predictive factor for renal function deterioration after partial nephrectomy: a retrospective case?control study
Usefulness of the mayo adhesive probability score as a predictive factor for renal function deterioration after partial nephrectomy: a retrospective case?control study
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梅奥粘附概率评分作为肾部分切除术后肾功能恶化的预测因素的有用性：回顾性病例对照研究
DOI：
10.1007/s11255-021-02986-5
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发表时间：
2021
影响因子：
2
通讯作者：
Kojima Yoshiyuki
中科院分区：
文献类型：
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作者：
Hata Junya;Matsuoka Yuta;Onagi Akifumi;Honda-Takinami Ruriko;Matsuoka Kanako;Sato Yuichi;Akaihata Hidenori;Ogawa Soichiro;Kataoka Masao;Hosoi Takayuki;Kojima Yoshiyuki
目的探讨肾周脂肪环境指标Mayo黏附概率评分是否可作为肾部分切除术后肾功能恶化的预测因素。术后3个月肾小球滤过率在 ≤ 为90%的保存率被定义为术后肾功能恶化。将这些患者分为两组(未恶化组和恶化组)。评估患者因素，包括Mayo黏附概率评分(肿瘤和健侧)和手术因素，以确定术后肾功能恶化的预测因素。结果37例(47.4%)肾部分切除患者术后肾功能恶化。单变量分析确定健侧Mayo黏附概率评分(p= 0.02)和热缺血时间(p<； 0.01)是术后肾功能恶化的预测指标。在多因素分析中，与单因素分析一样，健侧Mayo黏附概率评分(优势比：1.38[1.05~1.79]，p= 0.02)和热缺血时间(优势比：1.04[1.01~1.07]，p<； 0.01)与术后肾功能恶化显著相关。在接收操作特征曲线分析中，健侧Mayo黏附概率评分(截止值1.5；p= 0.02)和热缺血时间(截断值26.5min；p= 0.01)是术后3个月肾功能恶化的有意义的预测因素。结论健侧Mayo黏附概率评分和热缺血时间是肾部分切除术后肾功能恶化的有用预测因子。
PurposeWhether the Mayo adhesive probability score, an index of the perinephric fat environment, could be a predictive factor for renal function deterioration after partial nephrectomy was investigated.MethodsA retrospective case–control study of 78 patients who underwent laparoscopic partial nephrectomy was performed. An estimated glomerular filtration rate preservation rate at ≤ 90% at 3 months after surgery was defined as postoperative renal function deterioration. These patients were divided into two groups (non-deterioration and deterioration groups). Patient factors including Mayo adhesive probability scores (both tumor and unaffected sides) and surgical factors were evaluated to identify the predictors for postoperative renal function deterioration. The statistical analysis used univariate and multivariate logistic regression analyses.ResultsThirty-seven (47.4%) patients had postoperative renal function deterioration after partial nephrectomy. Univariate analysis identified Mayo adhesive probability score on the unaffected side (p= 0.02), and warm ischemia time (p< 0.01) as predictors of postoperative renal function deterioration. On multivariate analyses, Mayo adhesive probability score on the unaffected side (odds ratio: 1.38 [1.05–1.79],p= 0.02) and warm ischemia time (odds ratio: 1.04 [1.01–1.07],p< 0.01) were significantly associated with postoperative renal function deterioration as same as univariate analysis. On receive operating characteristic curve analysis, Mayo adhesive probability score on the unaffected side (cutoff value 1.5;p= 0.02) and warm ischemia time (cutoff value 26.5 min;p= 0.01) were significant predictors of renal function deterioration 3 month after surgery.ConclusionThe Mayo adhesive probability score on the unaffected side and warm ischemia time are useful predictors for renal function deterioration after partial nephrectomy.Trial registration number2019-249, January 21st, 2019, retrospectively registered.