Vibratory coherence as an alternative to radiography in assessing bone healing after osteodistraction.
Vibratory coherence as an alternative to radiography in assessing bone healing after osteodistraction.
复制标题
振动相干性作为放射线照相的替代方法来评估骨牵引后的骨愈合。
DOI：
10.1114/1.1454135
复制
发表时间：
2002
影响因子：
3.8
通讯作者：
Magin,RL
中科院分区：
文献类型：
--
作者：
El-Bialy,TH;Royston,TJ;Sakata,A;Magin,RL
牵引成骨术用于骨科，通过切割或折断骨头并随着新骨头填充中间空间而逐渐将两块骨头分开来延长骨头。需要对骨愈合程度进行早期评估，以实现正常功能而不会产生不良副作用。这项研究比较了用于评估 21 只兔子下颌骨牵引过程中骨愈合程度的不同技术。对于每只兔子，通过外科手术切割下颌骨，然后 72 小时后开始以每天 3 毫米的速度进行牵引。通过头部X光片上的体内光密度测量、整个牵引部位的体内（非破坏性）振动相干性测试、死后、离体（破坏性）三点弯曲机械测试以及死后、离体（破坏性）组织学检查来评估牵引部位的骨形成。统计分析包括方差分析和相关系数检验。研究结果显示，骨光密度和机械三点测试的结果与振动测试的结果高度正相关。振动测试的使用可以替代或增强放射线照相术的常规使用，以进行骨愈合的体内评估和监测。 ©2002 生物医学工程学会.PAC2002: 8780-y, 8719Rr
Distraction osteogenesis is used in orthopedics to lengthen bones by cutting or breaking the bone and gradually separating the two pieces as new bone fills the intervening space. There is a need for early assessment of the degree of bone healing that allows for normal functioning without unwanted side effects. This study compared different techniques used to evaluate the degree of bone healing during mandibular osteodistraction in 21 rabbits. For each rabbit, the mandible was cut in a surgical procedure and then 72 h later distraction began at a rate of 3 mm per day. Bone formation at the distraction site was assessed byin vivophotodensitometry on head radiographs, anin vivo(nondestructive) vibratory coherence test across the distraction site, a postmortem,ex vivo(destructive) three-point bending mechanical test, and by postmortem,ex vivo(destructive) histological examination. Statistical analyses included analysis of variance and correlation coefficient tests. The findings revealed that the results of bone photodensity and the mechanical three-point test are highly and positively correlated with the results of the vibration test. The use of the vibration test may provide a substitute for or augment the routine use of radiography forin vivoevaluation and monitoring of bone healing. ©2002 Biomedical Engineering Society.PAC2002: 8780-y, 8719Rr