Identification of occupational cancer risks in British Columbia: A population-based case-control study of 1129 cases of bladder cancer
Identification of occupational cancer risks in British Columbia: A population-based case-control study of 1129 cases of bladder cancer
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DOI：
10.1097/01.jom.0000169094.77036.1d
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发表时间：
2005-08-01
影响因子：
3.2
通讯作者：
Gallagher, RP
中科院分区：
文献类型：
--
作者：
Band, PR;Le, ND;Gallagher, RP
目的：收集15463例癌症患者的终生职业史、吸烟和饮酒情况。本报告介绍膀胱癌的职业危险因素。方法：采用配对病例-对照设计。所有病例都被诊断为膀胱癌，对照组是由所有其他癌症部位组成的内部控制，不包括肺癌和未知的原发癌。数据分析采用条件逻辑回归对匹配集数据和似然比检验。结果：在许多职业和行业中观察到膀胱癌风险过高，特别是那些涉及接触金属的行业，包括铝、油漆和溶剂、多环芳烃、柴油发动机排放和纺织品。结论：我们的研究结果与文献一致，并进一步表明暴露于二氧化硅和电磁场可能会增加膀胱癌的风险。
Objective: We collected information on lifetime occupational histories, smoking, and alcohol consumption from 15,463 incident cancer cases. Occupational risk factors for bladder cancer are presented in this report. Method: A matched case-control design was used. All cases were diagnosed with bladder cancers, with controls being internal controls consisting of all other cancer sites, excluding lung and unknown primary. Data were analyzed using conditional logistic regression for matched sets data and the likelihood ratio test. Results: Excess bladder cancer risks was observed in a number of occupation and industries, particularly those involving exposure to metals, including aluminum, paint and solvents, polycyclic aromatic hydrocarbons, diesel engine emissions, and textiles. Conclusions: The results of our study are in line with those from the literature and further suggest that exposure to silica and to electromagnetic fields may carry an increased risk of bladder cancer.