Tolerance for uncertainty and perceived risk among women receiving uninformative BRCA1/2 test results
Tolerance for uncertainty and perceived risk among women receiving uninformative BRCA1/2 test results
复制标题
DOI：
10.1002/ajmg.c.30104
复制
发表时间：
2006-11-15
影响因子：
3.1
通讯作者：
Schwartz, Marc D.
中科院分区：
文献类型：
--
作者：
O'Neill, Suzanne C.;Demarco, Tiffani;Schwartz, Marc D.
接受BRCA1/2基因检测结果不准确的女性面临着未来癌症风险的持续不确定性。本文前瞻性地研究了在收到无信息的BRCA1/2检测结果后，对不确定性的不耐受和感知到的乳腺癌风险对心理困扰的影响。64名接受无信息BRCA1/2突变检测结果的妇女完成了对不确定性不耐受、乳腺癌风险感知、癌症相关、基因检测和一般痛苦的测量。与癌症相关(δ R-2 = 0.18， P
Women who receive uninformative BRCA1/2 genetic test results face ongoing uncertainty about their future cancer risks. This article prospectively examined the influence of intolerance for uncertainty and perceived breast cancer risk on psychological distress following the receipt of uninformative BRCA1/2 test results. Sixty-four women who received uninformative BRCA1/2 mutation test results completed measures of Intolerance for Uncertainty, perceived breast cancer risk, and measures of cancer-related, genetic testing, and general distress. Cancer-related (Delta R-2 = 0.18, P