Classification of HHV-6A and HHV-6B as distinct viruses.
Classification of HHV-6A and HHV-6B as distinct viruses.
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DOI：
10.1007/s00705-013-1902-5
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发表时间：
2014-05
影响因子：
2.7
通讯作者：
Yoshikawa T
中科院分区：
文献类型：
--
作者：
Ablashi D;Agut H;Alvarez-Lafuente R;Clark DA;Dewhurst S;DiLuca D;Flamand L;Frenkel N;Gallo R;Gompels UA;Höllsberg P;Jacobson S;Luppi M;Lusso P;Malnati M;Medveczky P;Mori Y;Pellett PE;Pritchett JC;Yamanishi K;Yoshikawa T
人类疱疹病毒6型（HHV-6）发现后不久，就鉴定出了两种不同的变体，HHV-6A和HHV-6 B。2012年，国际病毒分类委员会（ICTV）将HHV-6A和HHV-6 B归类为单独的病毒。这篇综述概述了几个记录的流行病学，生物学和HHV-6A和HHV-6 B之间的免疫学区别，支持ICTV分类。现在需要利用病毒特异性临床和实验室检测来区分HHV-6A和HHV-6 B以进行进一步分类。为了明确HHV-6A和HHV-6 B之间的生物学和临床区别，本文敦促科学家和医生在可能的情况下，在所有未来的出版物中仔细区分HHV-6A和HHV-6 B。
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-6A and HHV-6B, which support the ICTV classification. The utilization of virus-specific clinical and laboratory assays for distinguishing HHV-6A and HHV-6B is now required for further classification. For clarity in biological and clinical distinctions between HHV-6A and HHV-6B, scientists and physicians are herein urged, where possible, to differentiate carefully between HHV-6A and HHV-6B in all future publications.