Cognitive screening among acute respiratory failure survivors: a cross-sectional evaluation of the Mini-Mental State Examination.
Cognitive screening among acute respiratory failure survivors: a cross-sectional evaluation of the Mini-Mental State Examination.
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急性呼吸衰竭幸存者中的认知筛查：小精神状态检查的横断面评估。
DOI：
10.1186/s13054-015-0934-5
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发表时间：
2015-05-05
期刊：
影响因子：
--
通讯作者：
NIH NHLBI ARDS Network
中科院分区：
文献类型：
--
作者：
Pfoh ER;Chan KS;Dinglas VD;Girard TD;Jackson JC;Morris PE;Hough CL;Mendez-Tellez PA;Ely EW;Huang M;Needham DM;Hopkins RO;NIH NHLBI ARDS Network
迷你精神状态检查（MMSE）是一种常见的认知筛查测试，但其在急性呼吸衰竭幸存者中识别损伤的效用尚不清楚。本研究的目的是评估急性呼吸衰竭幸存者的MMSE表现与同时给予详细的神经心理测试组。本横断面分析使用的数据来自ARDSNet长期结局研究（ALTOS）和觉醒与呼吸控制试验（ABC）。参与者为242例急性呼吸衰竭幸存者。ALTOS研究在出院后6个月和12个月进行MMSE和详细的神经心理测试，ABC研究在出院后3个月和12个月进行。将MMSE鉴定的总体认知障碍（评分<24）与神经心理测试鉴定的障碍进行比较。我们还将MMSE上的定向、注册、注意、记忆和语言领域与相应的神经心理学测试相匹配。评估两两相关性、敏感性、特异性、阳性预测值和阴性预测值以及一致性。MMSE和神经心理测试在整体认知障碍方面的一致性是公平的（42%到80%）。特异性极好（≥93%），但敏感性较差（19 ~ 37%）。MMSE域与相应的神经心理测试之间的相关性为弱至中度（6个月：r = 0.11至0.28；12个月：r = 0.09至0.34）。MMSE与神经心理领域的相关性最高的是6个月时的注意力（r = 0.28）和12个月时的语言（r = 0.34）。在急性呼吸衰竭幸存者中，与同时进行详细的神经心理测试相比，MMSE在检测认知障碍方面的敏感性较差。该人群的MMSE结果应谨慎解释。
The Mini-Mental State Examination (MMSE) is a common cognitive screening test, but its utility in identifying impairments in survivors of acute respiratory failure is unclear. The purpose of this study was to evaluate MMSE performance versus a concurrently administered detailed neuropsychological test battery in survivors of acute respiratory failure. This cross-sectional analysis used data from the ARDSNet Long Term Outcomes Study (ALTOS) and Awakening and Breathing Controlled Trial (ABC). Participants were 242 survivors of acute respiratory failure. The MMSE and detailed neuropsychological tests were administered at 6 and 12 months post-hospital discharge for the ALTOS study, and at hospital discharge, 3 and 12 months for the ABC study. Overall cognitive impairment identified by the MMSE (score <24) was compared to impairments identified by the neuropsychological tests. We also matched orientation, registration, attention, memory and language domains on the MMSE to the corresponding neuropsychological test. Pairwise correlations, sensitivity, specificity, positive and negative predictive values, and agreement were assessed. Agreement between MMSE and neuropsychological tests for overall cognitive impairment was fair (42 to 80%). Specificity was excellent (≥93%), but sensitivity was poor (19 to 37%). Correlations between MMSE domains and corresponding neuropsychological tests were weak to moderate (6 months: r = 0.11 to 0.28; 12 months: r = 0.09 to 0.34). The highest correlation between the MMSE and neuropsychological domains was for attention at 6 months (r = 0.28) and language at 12 months (r = 0.34). In acute respiratory failure survivors, the MMSE has poor sensitivity in detecting cognitive impairment compared with concurrently administered detailed neuropsychological tests. MMSE results in this population should be interpreted with caution.
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del妄作为重症疾病幸存者长期认知障碍的预测指标。
影响因子：
8.8
作者：
Girard TD;Jackson JC;Pandharipande PP;Pun BT;Thompson JL;Shintani AK;Gordon SM;Canonico AE;Dittus RS;Bernard GR;Ely EW
通讯作者：
Ely EW
DOI：
10.1097/ta.0b013e3182114f18
发表时间：
2011-04-01
影响因子：
--
作者：
Guillamondegui, Oscar D.;Richards, Justin E.;Obremskey, William T.
通讯作者：
Obremskey, William T.
DOI：
10.1164/rccm.201103-0503oc
发表时间：
2012-03-01
影响因子：
24.7
作者：
Bienvenu, Oscar J.;Colantuoni, Elizabeth;Needham, Dale M.
通讯作者：
Needham, Dale M.
DOI：
10.1097/ta.0b013e31802ce9bd
发表时间：
2007-01-01
影响因子：
--
作者：
Jackson, James C.;Obremskey, William;Ely, E. Wesley
通讯作者：
Ely, E. Wesley
影响因子：
76.2
作者：
Jackson, James C.;Pandharipande, Pratik P.;Girard, Timothy D.;Brummel, Nathan E.;Thompson, Jennifer L.;Hughes, Christopher G.;Pun, Brenda T.;Vasilevskis, Eduard E.;Morandi, Alessandro;Shintani, Ayumi K.;Hopkins, Ramona O.;Bernard, Gordon R.;Dittus, Robert S.;Ely, E. Wesley
通讯作者：
Ely, E. Wesley