Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex.
Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex.
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DOI：
10.1017/s0048577298961601
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发表时间：
1998-05
期刊：
影响因子：
3.7
通讯作者：
Marty G. Woldorff;S. Hillyard;C. Gallen;Scott R. Hampson;Floyd E. Bloom
中科院分区：
文献类型：
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作者：
Marty G. Woldorff;S. Hillyard;C. Gallen;Scott R. Hampson;Floyd E. Bloom
人们普遍认为，在150 - 200毫秒的负脑电位引起的偏差，强度较低的声音在一个重复的系列可以调制的注意。为了研究这种调制是否代表一个真正的注意力效应的不匹配负波（MMN）所产生的听觉皮层或注意力相关的活动从另一个大脑区域，我们记录的MMN和不匹配磁场（MMF）引起的这种偏差在双耳分听任务。异常的音调在出席的耳朵引起了一个相当大的MMF是很好地模拟作为一个双极源的听觉皮层。对无人看管的耳部异常者的MMN和MMF都高度减弱。这些研究结果支持这样的观点，即MMN/MMF引起的听觉皮层强度偏差，从而潜在的功能分析和失配检测过程，是不是强烈自动的，而是可以门控或抑制，如果注意力强烈集中在其他地方。
It is widely agreed that the negative brain potential elicited at 150-200 ms by a deviant, less intense sound in a repetitive series can be modulated by attention. To investigate whether this modulation represents a genuine attention effect on the mismatch negativity (MMN) arising from auditory cortex or attention-related activity from another brain region, we recorded both the MMN and the mismatch magnetic field (MMF) elicited by such deviants in a dichotic listening task. Deviant tones in the attended ear elicited a sizable MMF that was well modeled as a dipolar source in auditory cortex. Both the MMN and MMF to unattended-ear deviants were highly attenuated. These findings support the view that the MMN/MMF elicited in auditory cortex by intensity deviants, and thus the underlying feature-analysis and mismatch-detection processes, are not strongly automatic but rather can be gated or suppressed if attention is strongly focused elsewhere.