A rapid and sensitive method for detecting human cells in xenogeneic hosts.
A rapid and sensitive method for detecting human cells in xenogeneic hosts.
复制标题
一种快速、灵敏的检测异种宿主中人类细胞的方法。
DOI：
10.1097/00007890-199810150-00020
复制
发表时间：
1998
期刊：
影响因子：
6.2
通讯作者：
Hulsebosch,CE
中科院分区：
文献类型：
--
作者：
Zompa,EA;Moyer,MP;Cain,LD;Bottenstein,JE;Hulsebosch,CE
Xenografts, specifically transplantation of human cells into other species, are a valuable tool in preclinical transplantation experiments. A central issue is accurate identification of the grafted cells, particularly in cases in which cellular migration has occurred. We report that detection of grafted human cells can be achieved by in situ hybridization techniques using human centromeric probes which result in unambiguous nuclear labeling. The resulting reaction can be combined with immunocytochemical or histochemical techniques for cell-type characterization.
