A century of neuroscience discovery: reflecting on the Nobel Prize awarded to Golgi and Cajal in 1906.
A century of neuroscience discovery: reflecting on the Nobel Prize awarded to Golgi and Cajal in 1906.
复制标题
一个世纪的神经科学发现：反思 1906 年授予高尔基和卡哈尔的诺贝尔奖。
DOI：
10.1016/j.brainresrev.2007.07.001
复制
发表时间：
2007
影响因子：
--
通讯作者：
Morrison,JohnH
中科院分区：
文献类型：
--
作者：
Swanson,LarryW;Grant,Gunnar;Hökfelt,Tomas;Jones,EdwardG;Morrison,JohnH
By the late 1830s, when the cell theory was articulated by Theodor Schwann (1810–1882) and Matthias Schleiden (1804–1881), virtually everything we know today about human brain macroanatomy—what can be seen with the naked eye and scalpel, or in a functional MRI—had already been discovered. The great problem faced by nineteenth century neuroscience was the exact microanatomical relationship between one adult nerve cell and another. Drama at the Nobel Prize ceremony in 1906 centered on diametrically opposite theories about the essential nature of this interneuronal relationship, based, incredible as it may sound, on key evidence derived from the same technique. The players were, of course, Camillo Golgi (1843–1926) and Santiago Ramón y Cajal (1852–1934), and the critical method was the “black reaction” that Golgi first briefly documented in 1873.
