Wearable device signals and home blood pressure data across age, sex, race, ethnicity, and clinical phenotypes in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) study: a prospective, community-based observational study
Wearable device signals and home blood pressure data across age, sex, race, ethnicity, and clinical phenotypes in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) study: a prospective, community-based observational study
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DOI：
10.1016/s2589-7500(21)00138-2
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发表时间：
2021-11-01
影响因子：
30.8
通讯作者：
Kheterpal, Sachin
中科院分区：
文献类型：
--
作者：
Golbus, Jessica R.;Pescatore, Nicole A.;Kheterpal, Sachin
可穿戴技术已迅速进入消费市场，并具有医疗保健潜力；然而，针对不同人群的可穿戴设备数据很少。因此，我们旨在描述和比较不同年龄、性别、种族、民族和临床表型的关键可穿戴信号（即心率、步数和家庭血压测量）。方法在密歇根健康预测活动与临床轨迹（MIPACT）前瞻性观察研究中，我们招募了来自美国密歇根州安阿伯市密歇根医学院的参与者，并对他们进行了至少90天的随访。如果患者年龄在18岁或以上，英语流利，拥有iPhone 6或支持iOS版本的更新型号，并且在整个研究期间定期访问互联网，则将其纳入研究对象。所有参与者都配备了苹果手表系列3或4，欧姆龙Evolv无线血压监测仪和mydata帮助研究智能手机应用程序。参与者被要求每天佩戴手表12小时或更长时间，并完成每日或每周的任务，包括在家测量血压和呼吸任务。他们收集了心率、血压、步数和步行距离。研究分为两个阶段：45天密集收集阶段（第一阶段）；为期3年的纵向监测阶段（第二阶段）。在这里，我们报告了所有参与者的前90天数据，包括第一阶段的所有数据和第二阶段的前45天数据。参与者的电子健康记录被用来建立临床诊断以供分析。我们在2018年8月14日至2019年12月19日期间招募了6765名符合条件的参与者，其中6454名来自密歇根医学院的参与者完成了i期研究方案，并被纳入本分析（3482名[54%]女性和2972名[46%]男性；3657名[57%]白人参与者，其中1094名[17%]亚洲参与者和1090名[17%]黑人参与者）。在参与者佩戴智能手表的日子里，他们每天佩戴手表的时间中位数为15小时（IQR 14-17）。参与者在90天内共测量了1 107 320血压和202 198 347心率，每个参与者测量了172 （SD 50）血压和31 329 （SD 24 620）心率。平均收缩压为122毫米汞柱（SD 10），平均舒张压为77毫米汞柱（SD 8），其中167 312（15%）的测量结果收缩压高于140毫米汞柱或舒张压高于90毫米汞柱。平均静息心率为每分钟64次（SD 8）。血压和静息心率因性别、年龄、种族和民族而异，男性血压较高，65岁及以上的参与者心率较低
Background Wearable technology has rapidly entered consumer markets and has health-care potential; however, wearable device data for diverse populations are scarce. We therefore aimed to describe and compare key wearable signals (ie, heart rate, step count, and home blood pressure measurements) across age, sex, race, ethnicity, and clinical phenotypes.Methods In the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) prospective observational study, we enrolled participants from Michigan Medicine, Ann Abor, MI, USA, and followed them up for at least 90 days. Patients were included if they were aged 18 years or older, were fluent in English, owned an iPhone 6 or newer model with a supported iOS version, and had regular access to the internet throughout the study period. All participants were provided with an Apple Watch Series 3 or 4, an Omron Evolv Wireless Blood Pressure Monitor, and the MyDataHelps study smartphone application. Participants were asked to wear their watch for 12 h per day or longer and to do daily or weekly tasks, including home blood pressure measurements and breathing tasks. Heart rate, blood pressure, step counts, and distance walked were collected. The study was divided into two phases: an intensive 45-day collection phase (phase 1); and a 3-year longitudinal monitoring phase (phase 2). Here we report the first 90 days of data for all participants, which includes all of phase 1 and the first 45 days of phase 2. Participants' electronic health records were used to establish clinical diagnoses for analysis.Findings We enrolled 6765 eligible participants between Aug 14, 2018, and Dec 19, 2019, of whom 6454 participants from Michigan Medicine completed the phase 1 study protocol and were included in this analysis (3482 [54%] women and 2972 [46%] men; 3657 [57%] participants were White, with 1094 [17%] Asian and 1090 [17%] Black participants). On days when participants wore their smart watches, median daily watch wear time was 15middot5 h (IQR 14-17). Participants contributed a total of 1 107 320 blood pressure and 202 198 347 heart rate measurements over 90 days, with 172 (SD 50) blood pressure and 31 329 (SD 24 620) heart rate measurements per participant. Mean systolic blood pressure was 122 mm Hg (SD 10) and mean diastolic blood pressure was 77 mm Hg (SD 8), with 167 312 (15%) measurements having a systolic blood pressure higher than 140 mm Hg or diastolic blood pressure higher than 90 mm Hg. Mean resting heart rate was 64 beats per min (SD 8). Blood pressure and resting heart rate varied by sex, age, race, and ethnicity, with higher blood pressures in males and lower heart rate in participants aged 65 years or older (p