Geographic disparities in COVID-19 case rates are not reflected in seropositivity rates using a neighborhood survey in Chicago.
Geographic disparities in COVID-19 case rates are not reflected in seropositivity rates using a neighborhood survey in Chicago.
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DOI：
10.1016/j.annepidem.2021.10.006
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发表时间：
2022-03
影响因子：
5.6
通讯作者：
McDade TW
中科院分区：
文献类型：
--
作者：
Mustanski B;Saber R;Ryan DT;Benbow N;Madkins K;Hayford C;Newcomb ME;Schrock JM;Vaught LA;Reiser NL;Velez MP;Hsieh RR;Demonbreun AR;D'Aquila R;McNally EM;McDade TW
迄今为止，美国黑人和拉丁裔社区的COVID-19病例率高得不成比例，导致这些社区的住院治疗和死亡人数增加。这些发病率的差异在芝加哥不同种族和/或民族居民的社区比较中是明显的。差异可能是由于与贫困和其他健康社会决定因素相关的不良健康结果较多的社区出现较高的SARS-CoV-2感染流行率，或者由于相同的SARS-CoV-2感染流行率导致更高的发病率和死亡率。我们调查了芝加哥五对相邻的邮政编码，这些邮政编码的COVID-19发病率不同，以获取任何先前感染SARS-CoV-2的高度特异性和定量血清学证据，并与它们不同的COVID-19发病率进行比较。2020年夏天，在芝加哥第一波COVID-19大流行之后不久，互联网招募的参与者在家中自行收集了干血斑样本。相邻的邮政编码对COVID-19病例率差异很大，但抗sars - cov -2受体结合域IgG抗体的血清阳性率相似。总体而言，这些在COVID-19发病率非常不同的社区中暴露于SARS-CoV-2的可比发现与健康的社会决定因素以及与之相关的合并症是一致的，这导致了社区间COVID-19发病率的差异。
To date, COVID-19 case rates are disproportionately higher in Black and Latinx communities across the US, leading to more hospitalizations, and deaths in those communities. These differences in case rates are evident in comparisons of Chicago neighborhoods with differing race and/or ethnicities of their residents. Disparities could be due to neighborhoods with more adverse health outcomes associated with poverty and other social determinants of health experiencing higher prevalence of SARS-CoV-2 infection or due to greater morbidity and mortality resulting from equivalent SARS-CoV-2 infection prevalence. We surveyed five pairs of adjacent ZIP codes in Chicago with disparate COVID-19 case rates for highly specific and quantitative serologic evidence of any prior infection by SARS-CoV-2 to compare with their disparate COVID-19 case rates. Dried blood spot samples were self-collected at home by internet-recruited participants in summer 2020, shortly after Chicago's first wave of the COVID-19 pandemic. Pairs of neighboring ZIP codes with very different COVID-19 case rates had similar seropositivity rates for anti–SARS-CoV-2 receptor binding domain IgG antibodies. Overall, these findings of comparable exposure to SARS-CoV-2 across neighborhoods with very disparate COVID-19 case rates are consistent with social determinants of health, and the co-morbidities related to them, driving differences in COVID-19 rates across neighborhoods.
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影响因子：
6.4
作者：
Guthmiller JJ;Stovicek O;Wang J;Changrob S;Li L;Halfmann P;Zheng NY;Utset H;Stamper CT;Dugan HL;Miller WD;Huang M;Dai YN;Nelson CA;Hall PD;Jansen M;Shanmugarajah K;Donington JS;Krammer F;Fremont DH;Joachimiak A;Kawaoka Y;Tesic V;Madariaga ML;Wilson PC
通讯作者：
Wilson PC
DOI：
10.15585/mmwr.mm6915e1
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Ghinai I;Woods S;Ritger KA;McPherson TD;Black SR;Sparrow L;Fricchione MJ;Kerins JL;Pacilli M;Ruestow PS;Arwady MA;Beavers SF;Payne DC;Kirking HL;Layden JE
通讯作者：
Layden JE
影响因子：
82.9
作者：
Amanat F;Stadlbauer D;Strohmeier S;Nguyen THO;Chromikova V;McMahon M;Jiang K;Arunkumar GA;Jurczyszak D;Polanco J;Bermudez-Gonzalez M;Kleiner G;Aydillo T;Miorin L;Fierer DS;Lugo LA;Kojic EM;Stoever J;Liu STH;Cunningham-Rundles C;Felgner PL;Moran T;García-Sastre A;Caplivski D;Cheng AC;Kedzierska K;Vapalahti O;Hepojoki JM;Simon V;Krammer F
通讯作者：
Krammer F
影响因子：
4.9
作者：
Millett GA;Honermann B;Jones A;Lankiewicz E;Sherwood J;Blumenthal S;Sayas A
通讯作者：
Sayas A
影响因子：
3.7
作者：
McDade, Thomas W.;McNally, Elizabeth M.;Demonbreun, Alexis R.
通讯作者：
Demonbreun, Alexis R.