Effects of long-term nasal continuous positive airway pressure on C-reactive protein in patients with obstructive sleep apnea syndrome

Effects of long-term nasal continuous positive airway pressure on C-reactive protein in patients with obstructive sleep apnea syndrome
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DOI:
10.2169/internalmedicine.44.899
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发表时间:
2005-08-01
期刊:
影响因子:
1.2
通讯作者:
Horie, T
Horie, T
中科院分区:
医学4区
文献类型:
--
作者:
Akashiba, T;Akahoshi, T;Horie, T

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连续测定 9 名阻塞性睡眠呼吸暂停综合征 (OSAS) 患者在经鼻持续气道正压治疗前后的血清 C 反应蛋白 (CRP) 水平。 CRP 水平仅与治疗前的体重指数 (BMI) 显着相关。治疗 9 个月后,BMI 和 CRP 水平没有观察到显着变化。这些数据表明 OSAS 患者的 CRP 水平可能与肥胖相关,而不是 OSAS 本身。
Serum levels of C-reactive protein (CRP) were measured in 9 consecutive patients with obstructive sleep apnea syndrome (OSAS) before and after nasal continuous positive airway pressure treatment. CRP levels only displayed significant correlations with body mass index (BMI) before treatment. No significant changes were observed in BMI - and CRP levels after 9 months of treatment. These data suggest that CRP levels in patients with OSAS may be associated with obesity rather than OSAS itself.