Acute fibrinous and organizing pneumonia in a patient with HIV infection and Pneumocystis jiroveci pneumonia
Acute fibrinous and organizing pneumonia in a patient with HIV infection and Pneumocystis jiroveci pneumonia
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DOI：
10.1111/j.1440-1843.2010.01845.x
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发表时间：
2010-11-01
期刊：
影响因子：
6.9
通讯作者：
Kim, Woo Joo
中科院分区：
文献类型：
--
作者：
Heo, Jung Yeon;Song, Joon Young;Kim, Woo Joo
急性纤维化和机化性肺炎（AFOP）是一种以肺泡腔内纤维蛋白沉积为特征的小气道疾病。组织学模式被描述为隐源性机化性肺炎（COP）的变异。尽管COP偶尔在HIV感染患者中出现，但此前尚未在此类患者中报告过变异形式AFOP。本报告描述了一个有趣的情况下，AFOP的病人与艾滋病毒感染和肺孢子虫肺炎。AFOP是在皮质类固醇治疗逐渐减少后诊断的。本病例说明，非感染性肺浸润应考虑在肺部疾病的鉴别诊断与艾滋病毒感染的患者。
Acute fibrinous and organizing pneumonia (AFOP) is a disease of the small airways that is characterized by deposition of fibrin within the alveolar spaces. The histological pattern is described as a variant of cryptogenic organizing pneumonia (COP). Although COP has been occasionally described in patients with HIV infection, the variant form, AFOP, has not been previously reported in such patients. This report describes an intriguing case of AFOP in a patient with HIV infection and Pneumocystis jiroveci pneumonia. AFOP was diagnosed after tapering of corticosteroid therapy. This case illustrates that non-infectious pulmonary infiltrates should be considered in the differential diagnosis of lung disease in patients with HIV infection.